PPP2R2D

Gene Symbol PPP2R2D
Entrez Gene 55844
Alt Symbol MDS026
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit B, delta
Other Description PP2A subunit B isoform B55-delta|PP2A subunit B isoform PR55-delta|PP2A subunit B isoform R2-delta|PP2A subunit B isoform delta|protein phosphatase 2, regulatory subunit B, delta isoform|serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Swissprots Q5SQJ2 Q9P1Y7 A8KAK0 Q66LE6
Accessions EAW49145 EAW49146 EAW49147 Q66LE6 AB040974 BAA96065 AF220046 AAF67639 AI521071 AK000402 AK001483 BAG50921 AK293065 BAF85754 BC047379 AAH47379 BC058076 AAH58076 BC060885 BC072402 AAH72402 BQ023669 HQ447504 ADQ31990 XM_005277927 XP_005277984 XM_006717914 XP_006717977 XM_006717915 XP_006717978 XM_011539950 XP_011538252 XM_011539951 XP_011538253 XR_945786 NM_001003656 NM_001291310 NP_001278239 NM_018461 NP_060931 NR_033191
Function B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55- delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Dopaminergic synapse, mRNA surveillance pathway, PI3K-Akt signaling pathway, Hepatitis C, Hippo signaling pathway

Human PPP2R2D full length protein - ab163251 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163251 on a 12.5% SDS-PAGE stained with Coomassie Blue.

PPP2R2D Antibody Blocking Peptide - LS-E20339 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PPP2R2D Recombinant Protein - H00055844-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Ppp2r2d Blocking Peptide - 33R-8132 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PPP2R2D - H00055844-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PPP2R2D - H00055844-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Recombinant Human PPP2R2D - PPP2R2D-1206H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subu - CSB-YP727750HU CSB-EP727750HU CSB-BP727750HU CSB-MP727750HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PPP2R2D Recombinant Protein Antigen - NBP2-33379PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PPP2R2D Peptide, Human - M34GP12275H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D), Recombinant Protein - MBS1313653 from MyBioSource

Category Protein
Prices $1,235.00, $1,235.00, $1,455.00, $1,455.00, $2,005.00, $2,005.00, $2,470.00, $2,470.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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