PPP2R2D

Gene Symbol	PPP2R2D
Entrez Gene	55844
Alt Symbol	MDS026
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 2, regulatory subunit B, delta
Other Description	PP2A subunit B isoform B55-delta|PP2A subunit B isoform PR55-delta|PP2A subunit B isoform R2-delta|PP2A subunit B isoform delta|protein phosphatase 2, regulatory subunit B, delta isoform|serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Swissprots	Q5SQJ2 Q9P1Y7 A8KAK0 Q66LE6
Accessions	EAW49145 EAW49146 EAW49147 Q66LE6 AB040974 BAA96065 AF220046 AAF67639 AI521071 AK000402 AK001483 BAG50921 AK293065 BAF85754 BC047379 AAH47379 BC058076 AAH58076 BC060885 BC072402 AAH72402 BQ023669 HQ447504 ADQ31990 XM_005277927 XP_005277984 XM_006717914 XP_006717977 XM_006717915 XP_006717978 XM_011539950 XP_011538252 XM_011539951 XP_011538253 XR_945786 NM_001003656 NM_001291310 NP_001278239 NM_018461 NP_060931 NR_033191
Function	B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55- delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Top Pathways	Dopaminergic synapse, mRNA surveillance pathway, PI3K-Akt signaling pathway, Hepatitis C, Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PP2A-B55-δ siRNA (h) - sc-106433 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PP2A-B55-δ shRNA Plasmid (h) - sc-106433-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PP2A-B55-δ shRNA (h) Lentiviral Particles - sc-106433-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU160441 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0623 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP1037 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0622 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0624 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP1038 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17294 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17294 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05525 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr05525

PPP2R2D siRNA (Human) - CRJ0965 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PPP2R2D (NM_018461.3) - SHH381420 from Creative biogene Category siRNA Species Reactivities Human

Human PPP2R2D siRNA - orb271466 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PPP2R2D shRNA Plasmid (Human) - CHJ0965 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PPP2R2D miRNA 3'UTR clone - MiUTR3H-13099 from Creative biogene Species Reactivities Human

Search more