PPL

Gene Symbol PPL
Entrez Gene 5493
Alt Symbol -
Species Human
Gene Type protein-coding
Description periplakin
Other Description 190 kDa paraneoplastic pemphigus antigen|195 kDa cornified envelope precursor protein
Swissprots Q14C98 O60437 O60314 O60454
Accessions AAD17459 CAP07522 CAP11490 CAR97104 CAT82362 EAW85248 O60437 AB011140 BAA25494 AF001691 AAC17738 AF013717 AAC39668 AK295623 BAH12130 AW582622 BC114620 AAI14621 BM673980 XM_006720902 XP_006720965 NM_002705 NP_002696
Function Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling. {ECO:0000269|PubMed:9412476}.
Subcellular Location Cell junction, desmosome {ECO:0000269|PubMed:9412476}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9412476}. Cell membrane {ECO:0000250}. Nucleus {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Associated with desmosomes and intermediate filaments.
Tissue Specificity Expressed in stratified squamous epithelia and in some other epithelia. {ECO:0000269|PubMed:9412476, ECO:0000269|PubMed:9521878}.

periplakin (G-1) - sc-365530 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
periplakin (G-1): sc-365530. Western blot analysis of periplakin expression in Hep G2 whole cell lysate.

periplakin (AE11) - sc-80605 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

periplakin (H-200) - sc-50449 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
periplakin (H-200): sc-50449. Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing membrane and cytoplasmic staining of squamous epithelial cells.

periplakin (C-20) - sc-16754 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
periplakin (C-20): sc-16754. Western blot analysis of periplakin expression in human skin tissue extract.

Anti-Periplakin antibody - ab72422 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab72422 stained SW480 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab72422 at 1µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Alexa Fluor® 488 goat anti- rabbit (ab150081) IgG (H+L) preadsorbed, used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-Periplakin antibody - ab176968 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Periplakin antibody (ab176968) at 1/1000 dilution + Human fetal skin lysate

Anti-Periplakin antibody - ab196256 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
Anti-Periplakin antibody (ab196256) at 1/1000 dilution + Human fetal skin lysate

Anti-Periplakin antibody - ab123090 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Periplakin antibody (ab123090) at 1/100 dilution + T47D cell line lysates at 35 µg

Anti-Periplakin antibody [EPR8296] - ab131269 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8296
All lanes : Anti-Periplakin antibody [EPR8296] (ab131269) at 1/1000 dilutionLane 1 : HACAT lysateLane 2 : Human skin lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-PPL / Periplakin Antibody (aa1439-1716, Biotin) - LS-C298607 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPL / Periplakin Antibody (Internal, clone EPR8296) - LS-C154586 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8296
IHC of paraffin-embedded human skin tissue using anti-PPL / Periplakin antibody.

Anti-PPL / Periplakin Antibody (aa1439-1716, FITC) - LS-C301403 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPL / Periplakin Antibody (aa1300-1331) - LS-C324224 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPL / Periplakin Antibody (aa1439-1716, FITC) - LS-C301901 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPL / Periplakin Antibody (aa1150-1200) - LS-C287863 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse and Rat Periplakin/PPL by Western Blot. Samples: Whole cell lysate (50 ug) from NIH3T3, TCMK-1, 4T1, CT26.WT, and rat C6 cells. Antibodies: Affinity purified rabbit anti-Periplakin/PPL antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-PPL / Periplakin Antibody (aa1439-1716) - LS-C295805 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PPL / Periplakin.

Anti-PPL / Periplakin Antibody (aa1439-1716) - LS-C295803 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PPL / Periplakin.

Anti-PPL / Periplakin Antibody (aa1301-1330) - LS-C163906 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PPL Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PPL / Periplakin Antibody (aa1501-1754) - LS-C315001 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PPL / Periplakin.

Anti-PPL / Periplakin Antibody - LS-C346172 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of U20S cell using PPL antibody.

Anti-PPL / Periplakin Antibody (aa1150-1200) - LS-C90075 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-PPL / Periplakin Antibody - LS-C193742 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Guinea Pig
Clonality Polyclonal

Anti-PPL / Periplakin Antibody (aa1300-1331, AP) - LS-C266863 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPL / Periplakin Antibody (aa1300-1331, APC) - LS-C266864 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPL / Periplakin Antibody (aa1300-1331, Biotin) - LS-C266865 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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