FAIM2

Gene Symbol FAIM2
Entrez Gene 23017
Alt Symbol LFG, LFG2, NGP35, NMP35, TMBIM2
Species Human
Gene Type protein-coding
Description Fas apoptotic inhibitory molecule 2
Other Description neural membrane protein 35|protein lifeguard 2|transmembrane BAX inhibitor motif-containing protein 2
Swissprots Q9BWQ8 Q9UJY9 B3KR08 Q9Y2F7 A8K1W6
Accessions EAW58103 EAW58104 Q9BWQ8 AB023167 BAA76794 AF190461 AAF06327 AK090728 BAG52220 AK290031 BAF82720 AL707764 BC000051 AAH00051 BX647219 HQ448007 ADQ32488 XM_005268730 XP_005268787 NM_012306 NP_036438
Function Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. {ECO:0000269|PubMed:10535980, ECO:0000269|PubMed:17635665}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane raft {ECO:0000269|PubMed:17635665}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}.
Tissue Specificity Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus. {ECO:0000269|PubMed:10535980, ECO:0000269|PubMed:20336406}.

FAIM2 (H-7) - sc-398737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FAIM2 (H-7): sc-398737. Western blot analysis of FAIM2 expression in non-transfected: sc-117752 (A) and human FAIM2 transfected: sc-371178 (B) 293T whole cell lysates.

FAIM2 (E-15) - sc-167775 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FAIM2 (H-72) - sc-135120 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FAIM2 (H-72): sc-135120. Western blot analysis of FAIM2 expression in non-transfected: sc-117752 (A) and human FAIM2 transfected: sc-371178 (B) 293T whole cell lysates.

FAIM2 (H-21) - sc-130663 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
FAIM2 (H-21): sc-130663. Western blot analysis of FAIM2 expression in human brain tissue extract in the absence (A) and the presence (B) of immunizing peptide, mouse brain (C) and rat brain (D) tissue extracts.

Anti-FAIM2 antibody - ab194435 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-FAIM2 antibody (ab194435) at 1/1000 dilution + recombinant immunogen at 0.2 µg

Anti-FAIM2 antibody - ab64187 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Ab64187 (5ug/ml) staining human FAIM2 in human brain, cortex tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

Anti-FAIM2 antibody - ab58912 from Abcam

Prices $359.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-FAIM2 antibody (ab58912) at 0.5 µg/mlLane 2 : Anti-FAIM2 antibody (ab58912) at 1 µg/mlLane 1 : EL4 cell lysateLane 2 : EL4 cell lysateLysates/proteins at 15 µg per lane.

Anti-FAIM2 antibody - ab129689 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FAIM2 antibody (ab129689) at 1/100 dilution + U251 cell line lysate at 35 µg

Anti-FAIM2 antibody - ab72113 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lanes 1 - 2 : Anti-FAIM2 antibody (ab72113) at 2 µg/mlLane 3 : Anti-FAIM2 antibody (ab72113) at 1 µg/mlLane 4 : Anti-FAIM2 antibody (ab72113) at 0.5 µg/mlLane 1 : Human brain tissue lysateLane 2 : Human brain tissue lysate with Immunizing peptideLane 3 : Mouse brain tissue lysateLane 4 : Rat brain tissue lysate

Anti-FAIM2 / LIFEGUARD Antibody (N-Terminus) IHC-plus™ - LS-B567 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FAIM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B567 concentration 5 ug/ml.

Anti-FAIM2 / LIFEGUARD Antibody (aa1-50) IHC-plus™ - LS-B1782 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FAIM2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1782 concentration 10 ug/ml.

Anti-FAIM2 / LIFEGUARD Antibody (aa76-105, AP) - LS-C235144 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody (aa76-105, APC) - LS-C235143 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody (aa76-105, Biotin) - LS-C235145 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody (aa76-105, PE) - LS-C235150 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody (aa76-105, FITC) - LS-C235146 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody (aa75-105) - LS-C321267 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody (aa76-105, Azide-free, HRP) - LS-C249954 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody - LS-C307962 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FAIM2 / LIFEGUARD Antibody - LS-C341947 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FAIM2 / LIFEGUARD Antibody (aa20-69) - LS-C187339 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FAIM2 / LIFEGUARD antibody Western Blot of HepG2. Antibody dilution: 1 ug/ml.

Anti-FAIM2 / LIFEGUARD Antibody (aa76-105) - LS-C165922 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FAIM2 Antibody western blot of U251 cell line lysates (35 ug/lane). The FAIM2 antibody detected the FAIM2 protein (arrow).

FAIM2 Antibody - NBP2-24713 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

FAIM2 Antibody - NBP1-39736 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: FAIM2 Antibody [NBP1-39736] - Staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

FAIM2 Antibody - NBP1-77298 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FAIM2 Antibody [NBP1-77298] - Western blot analysis of FAIM2 in EL4 cell lysate with FAIM2 antibody at (A) 0.5 and (B) 1 ug/mL.
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