FAIM2

Gene Symbol	FAIM2
Entrez Gene	23017
Alt Symbol	LFG, LFG2, NGP35, NMP35, TMBIM2
Species	Human
Gene Type	protein-coding
Description	Fas apoptotic inhibitory molecule 2
Other Description	neural membrane protein 35|protein lifeguard 2|transmembrane BAX inhibitor motif-containing protein 2
Swissprots	Q9BWQ8 Q9UJY9 B3KR08 Q9Y2F7 A8K1W6
Accessions	EAW58103 EAW58104 Q9BWQ8 AB023167 BAA76794 AF190461 AAF06327 AK090728 BAG52220 AK290031 BAF82720 AL707764 BC000051 AAH00051 BX647219 HQ448007 ADQ32488 XM_005268730 XP_005268787 NM_012306 NP_036438
Function	Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. {ECO:0000269|PubMed:10535980, ECO:0000269|PubMed:17635665}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane raft {ECO:0000269|PubMed:17635665}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}.
Tissue Specificity	Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus. {ECO:0000269|PubMed:10535980, ECO:0000269|PubMed:20336406}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FAIM2 full length protein - ab161504 from Abcam Category Protein Source Wheat germ Species Human

FAIM2 / LIFEGUARD Antibody Blocking Peptide - LS-E4312 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FAIM2 / LIFEGUARD Antibody Blocking Peptide - LS-E29936 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

FAIM2 / LIFEGUARD Antibody Blocking Peptide - LS-E23730 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FAIM2 Protein - H00023017-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FAIM2 Blocking Peptide - NBP1-77298PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

FAIM2-Antibody-Center-Blocking-Peptide - BP16603c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FAIM2 Blocking Peptide - abx063753 from Abbexa Category Peptide Species Human

FAIM2 - H00023017-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FAIM2 - H00023017-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FAIM2 Control Peptide - AP30495CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

FAIM2 Peptide - 2285P from ProSci Category Peptide Species Human

FAIM2 fusion protein - ag7366 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

FAIM2 fusion protein - Ag7479 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human FAIM2, GST-tagged - FAIM2-12646H from Creative Biomart Category Protein Source E.coli Species Human

FAIM2 Blocking Peptide - CBP2559 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

FAIM2 Protein - abx163718 from Abbexa Category Protein Species Human

FAIM2 - TP300196 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FAIM2 Recombinant Protein Antigen - NBP2-33537PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FAIM2 Recombinant Protein Antigen - NBP1-81456PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FAIM2 Peptide, Human - M34GP05206H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein lifeguard 2 (FAIM2), Recombinant Protein - MBS7014502 from MyBioSource Category Protein Prices $1,125.00, $2,115.00, $3,320.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Recombinant Human FAIM2 Protein, GST-tagged - FAIM2-3656H from Creative Biomart Category Protein Source Wheat Germ Species Human

Search more