FAIM2

Gene Symbol FAIM2
Entrez Gene 23017
Alt Symbol LFG, LFG2, NGP35, NMP35, TMBIM2
Species Human
Gene Type protein-coding
Description Fas apoptotic inhibitory molecule 2
Other Description neural membrane protein 35|protein lifeguard 2|transmembrane BAX inhibitor motif-containing protein 2
Swissprots Q9BWQ8 Q9UJY9 B3KR08 Q9Y2F7 A8K1W6
Accessions EAW58103 EAW58104 Q9BWQ8 AB023167 BAA76794 AF190461 AAF06327 AK090728 BAG52220 AK290031 BAF82720 AL707764 BC000051 AAH00051 BX647219 HQ448007 ADQ32488 XM_005268730 XP_005268787 NM_012306 NP_036438
Function Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. {ECO:0000269|PubMed:10535980, ECO:0000269|PubMed:17635665}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane raft {ECO:0000269|PubMed:17635665}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}.
Tissue Specificity Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus. {ECO:0000269|PubMed:10535980, ECO:0000269|PubMed:20336406}.

FAIM2 CRISPR/Cas9 KO Plasmid (h) - sc-404103 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 HDR Plasmid (h) - sc-404103-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 Double Nickase Plasmid (h) - sc-404103-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 Double Nickase Plasmid (h2) - sc-404103-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 CRISPR Activation Plasmid (h) - sc-404103-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 CRISPR Activation Plasmid (h2) - sc-404103-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 Lentiviral Activation Particles (h) - sc-404103-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 Lentiviral Activation Particles (h2) - sc-404103-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAIM2 siRNA (h) - sc-95999 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAIM2 shRNA Plasmid (h) - sc-95999-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAIM2 shRNA (h) Lentiviral Particles - sc-95999-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAIM2 RNAi - H00023017-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU027521 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8101 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8101 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FAIM2 siRNA (Human) - CRH7933 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FAIM2 - MBS8203669 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FAIM2 shRNA Plasmid (Human) - CHH7933 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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