C1RL

Gene Symbol C1RL
Entrez Gene 51279
Alt Symbol C1RL1, C1RLP, C1r-LP, CLSPa
Species Human
Gene Type protein-coding
Description complement component 1, r subcomponent-like
Other Description C1r-like protein|C1r-like serine protease analog protein|complement C1r subcomponent-like protein|complement C1r-like proteinase
Swissprots Q9NZP8 Q53GX9
Accessions EAW88685 EAW88686 Q9NZP8 AF178985 AAF44349 AK024084 BAB14819 AK222802 BAD96522 AK314299 AW450562 BC062428 AAH62428 BC156780 AAI56781 DB113812 DR004214 HY062376 XM_005253386 XP_005253443 XM_005253387 XP_005253444 XM_006719084 XP_006719147 XM_006719085 XP_006719148 XM_011520688 XP_011518990 NM_001297640 NP_001284569 NM_001297642 NP_001284571 NM_001297643 NP_001284572 NM_016546 NP_057630
Function Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. {ECO:0000269|PubMed:15358180, ECO:0000269|PubMed:15385675, ECO:0000269|PubMed:15527420}.
Subcellular Location Secreted {ECO:0000269|PubMed:15358180}.
Tissue Specificity Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV- 3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level). {ECO:0000269|PubMed:15358180, ECO:0000269|PubMed:15527420}.

Anti-C1RL antibody - ab123797 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-C1RL antibody (ab123797) at 1/100 dilution + Jurkat cell line lysates at 35 µg

Anti-C1RL antibody - ab136685 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-C1RL antibody (ab136685) at 1 µg/ml + Human Fetal Liver lysate at 10 µg

Complement Component C1rLP Antibody - AF3990 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Complement Component C1rLP Antibody (393608) - MAB3676 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 393608

Complement Component C1rLP Antibody - AF3676 from Novus Biologicals

Prices $365.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Complement Component C1rLP Antibody - NBP1-88314 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C1RL Antibody [NBP1-88314] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

Complement Component C1rLP Antibody - H00051279-B01P-50ug from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

C1RL Polyclonal Antibody - bs-15087R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15087R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15087R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15087R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15087R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, Cy3 Conjugated - bs-15087R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, Cy5 Conjugated - bs-15087R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, Cy5.5 Conjugated - bs-15087R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, Cy7 Conjugated - bs-15087R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, FITC Conjugated - bs-15087R-FITC from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, Biotin Conjugated - bs-15087R-Biotin from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C1RL Polyclonal Antibody, HRP Conjugated - bs-15087R-HRP from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-C1RL antibody produced in rabbit - HPA011338 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-C1RL: <B>Cat. No. HPA011338</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human stomach shows strong cytoplasmic positivity in glandular cells.

ANTI-C1RL (CENTER) antibody produced in rabbit - SAB1304604 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C1RL (Center): <B>Cat. No. SAB1304604</B>: C1RL Antibody (Center) western blot analysis in Jurkat cell line lysates (35 μg/lane).

C1RL Antibody - middle region (ARP67407_P050) - ARP67407_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1RL-Antibody-Center - AP16193c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
C1RL Antibody (Center) (Cat. #AP16193c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the C1RL antibody detected the C1RL protein (arrow).

C1RL Antibody - middle region (OAAB11591) - OAAB11591 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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