C1RL

Gene Symbol C1RL
Entrez Gene 51279
Alt Symbol C1RL1, C1RLP, C1r-LP, CLSPa
Species Human
Gene Type protein-coding
Description complement component 1, r subcomponent-like
Other Description C1r-like protein|C1r-like serine protease analog protein|complement C1r subcomponent-like protein|complement C1r-like proteinase
Swissprots Q9NZP8 Q53GX9
Accessions EAW88685 EAW88686 Q9NZP8 AF178985 AAF44349 AK024084 BAB14819 AK222802 BAD96522 AK314299 AW450562 BC062428 AAH62428 BC156780 AAI56781 DB113812 DR004214 HY062376 XM_005253386 XP_005253443 XM_005253387 XP_005253444 XM_006719084 XP_006719147 XM_006719085 XP_006719148 XM_011520688 XP_011518990 NM_001297640 NP_001284569 NM_001297642 NP_001284571 NM_001297643 NP_001284572 NM_016546 NP_057630
Function Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. {ECO:0000269|PubMed:15358180, ECO:0000269|PubMed:15385675, ECO:0000269|PubMed:15527420}.
Subcellular Location Secreted {ECO:0000269|PubMed:15358180}.
Tissue Specificity Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV- 3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level). {ECO:0000269|PubMed:15358180, ECO:0000269|PubMed:15527420}.

C1RL-Antibody-Center-Blocking-Peptide - BP16193c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

C1RL fusion protein - ag20488 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

C1RL fusion protein - Ag20324 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human Complement C1r subcomponent-like protein(C1RL) - CSB-YP882160HU CSB-EP882160HU CSB-BP882160HU CSB-MP882160HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

C1RL (full length, N-term HIS tag) - TP760613 from Acris Antibodies

Category Protein
Prices $199.00
Sizes 50 µg
Source E. coli
Species Human
Complement component 1, r subcomponent-like (C1RL), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Complement Component C1rLP Recombinant Protein Antigen - NBP1-88314PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

C1RL-Antibody-N-term-Blocking-Peptide - BP7603a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

C1RL-Antibody-Center-Blocking-Peptide - BP7603c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

C1RL Peptide, Human - M34GP01935H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Complement C1r subcomponent-like protein (C1RL), Recombinant Protein - MBS1368303 from MyBioSource

Category Protein
Prices $1,230.00, $1,230.00, $1,450.00, $1,450.00, $2,000.00, $2,000.00, $2,465.00, $2,465.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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