TMPRSS11D

Gene Symbol TMPRSS11D
Entrez Gene 9407
Alt Symbol HAT
Species Human
Gene Type protein-coding
Description transmembrane protease, serine 11D
Other Description airway trypsin like protease|airway trypsin-like protease|transmembrane protease serine 11D
Swissprots O60235 Q08AF6
Accessions AAY40996 EAX05559 O60235 AB002134 BAA28691 AK094054 AK290289 BAF82978 AK296853 BAG59419 AL603214 BC033295 BC125195 AAI25196 BC125196 AAI25197 XM_005265710 XP_005265767 NM_004262 NP_004253
Function May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. {ECO:0000269|PubMed:23536651, ECO:0000269|PubMed:24227843}.
Subcellular Location Cell membrane; Single-pass type II membrane protein. Note=Activated by cleavage and secreted.
Tissue Specificity Located in the cells of the submucosal serous glands of the bronchi and trachea.

TMPRSS11D CRISPR/Cas9 KO Plasmid (h) - sc-407568 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D HDR Plasmid (h) - sc-407568-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D Double Nickase Plasmid (h) - sc-407568-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D Double Nickase Plasmid (h2) - sc-407568-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D CRISPR Activation Plasmid (h) - sc-407568-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D CRISPR Activation Plasmid (h2) - sc-407568-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D Lentiviral Activation Particles (h) - sc-407568-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D Lentiviral Activation Particles (h2) - sc-407568-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMPRSS11D siRNA (h) - sc-89121 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TMPRSS11D shRNA Plasmid (h) - sc-89121-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TMPRSS11D shRNA (h) Lentiviral Particles - sc-89121-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU038361 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2203 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2203 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TMPRSS11D siRNA (Human) - CRH6236 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMPRSS11D - MBS8241267 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TMPRSS11D (NM_004262.2) - SHH431404 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TMPRSS11D(NM_004262.2) - SHL082630 from Creative biogene

Category siRNA
Species Reactivities Human

Human TMPRSS11D siRNA - orb266738 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMPRSS11D shRNA Plasmid (Human) - CHH6236 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TMPRSS11D miRNA 3'UTR clone - MiUTR1H-10574 from Creative biogene

Species Reactivities Human
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