TMPRSS11D

Gene Symbol	TMPRSS11D
Entrez Gene	9407
Alt Symbol	HAT
Species	Human
Gene Type	protein-coding
Description	transmembrane protease, serine 11D
Other Description	airway trypsin like protease\|airway trypsin-like protease\|transmembrane protease serine 11D
Swissprots	O60235 Q08AF6
Accessions	AAY40996 EAX05559 O60235 AB002134 BAA28691 AK094054 AK290289 BAF82978 AK296853 BAG59419 AL603214 BC033295 BC125195 AAI25196 BC125196 AAI25197 XM_005265710 XP_005265767 NM_004262 NP_004253
Function	May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. {ECO:0000269\|PubMed:23536651, ECO:0000269\|PubMed:24227843}.
Subcellular Location	Cell membrane; Single-pass type II membrane protein. Note=Activated by cleavage and secreted.
Tissue Specificity	Located in the cells of the submucosal serous glands of the bronchi and trachea.

TMPRSS11D (A-14) - sc-104700 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TMPRSS11D (E-12) - sc-104701 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TMPRSS11D (E-12): sc-104701. Western blot analysis of TMPRSS11D expression in HeLa (A), Hep G2 (B) and NCI-H460 (C) whole cell lysates.

TMPRSS11D (S-12) - sc-104707 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TMPRSS11D (I-13) - sc-104703 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TMPRSS11D (B-24) - sc-134099 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

TMPRSS11D (B-24): sc-134099. Western blot analysis of TMPRSS11D expression in Hep G2 whole cell lysate.

Anti-TMPRSS11D antibody - ab127031 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TMPRSS11D antibody (ab127031) at 1/500 dilution + HepG2 whole cell lysate at 30 µg

Anti-TMPRSS11D antibody - ab168937 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-TMPRSS11D antibody (ab168937) at 1/500 dilutionLane 1 : HEK293T cells transfected with empty vectorLane 2 : HEK293T cells transfected with human TMPRSS11DLane 3 : HEK293T cells transfected with rhesus macaque TMPRSS11DLane 4 : HEK293T cells transfected with cynomolgus macaque TMPRSS11DLysates/proteins at 20 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG polyclonal at 1/10000 dilutionPerformed under reducing conditions.

Anti-TMPRSS11D antibody - Catalytic domain - ab65884 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-TMPRSS11D antibody - Catalytic domain (ab65884) at 1/5000 dilutionLane 1 : 80ng Recombinant Human TMPRSS11DLane 2 : 40ng Recombinant Human TMPRSS11DLane 3 : 20ng Recombinant Human TMPRSS11DLane 4 : 10ng Recombinant Human TMPRSS11DLane 5 : 5ng Recombinant Human TMPRSS11D

Anti-TMPRSS11D antibody - Cytoplasmic domain - ab65882 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-TMPRSS11D antibody - Cytoplasmic domain (ab65882) at 1/5000 dilutionLane 1 : HT 1080 lysate - Serum FreeLane 2 : HT 1080 lysate treated with TPALane 3 : HT 1080 lysate treated with IL1 betaLane 4 : HT 1080 lysate treated with TNF alphaLysates/proteins at 30 µl per lane.

Anti-TMPRSS11D antibody - SEA Domain - ab65883 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-TMPRSS11D antibody - SEA Domain (ab65883) at 1/5000 dilutionLane 1 : 80ng recombinant TMPRSS11DLane 2 : 40ng recombinant TMPRSS11DLane 3 : 20ng recombinant TMPRSS11DLane 4 : 10ng recombinant TMPRSS11DLane 5 : 5ng recombinant TMPRSS11D

Anti-TMPRSS11D / HAT Antibody - LS-C36596 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-TMPRSS11D / HAT Antibody (aa261-272) - LS-C108130 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-TMPRSS11D / HAT Antibody (aa288-337) - LS-C111096 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

TMPRSS11D / HAT antibody Western Blot of HepG2.

Anti-TMPRSS11D / HAT Antibody - LS-C155493 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

IHC of paraffin-embedded Breast ca, using TMPRSS11D antibody at 1:250 dilution.

Anti-TMPRSS11D / HAT Antibody (aa51-100) - LS-C80890 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

TMPRSS11D antibody LS-C80890 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.

Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody (337029) - MAB2695 from Novus Biologicals

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clonality	Monoclonal
Clone	337029

Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody - NBP1-62545 from Novus Biologicals

Prices	$139.00, $299.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody [NBP1-62545] - HepG2 cell lysate, concentration 2.5 ug/ml.

Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody - NBP2-20668 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: TMPRSS11D Antibody [NBP2-20668] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE gel, diluted at 1:500.

Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody - NBP1-69558 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: TMPRSS11D Antibody [NBP1-69558] - This Anti-TMPRSS11D antibody was used in Western Blot of 293T tissue lysate at a concentration of 1ug/ml.

Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody - H00009407-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody [H00009407-B01] - analysis of TMPRSS11D expression in transfected 293T cell line by TMPRSS11D MaxPab polyclonal antibody (B01). Lane 1: TMPRSS11D transfected lysate (46.30 KDa). Lane 2: Non-transfected lysate.

Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody - H00009407-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody [H00009407-B01P] - Analysis of TMPRSS11D expression in transfected 293T cell line by TMPRSS11D polyclonal antibody. Lane 1: TMPRSS11D transfected lysate(45.98 KDa). Lane 2: Non-transfected lysate.

Airway Trypsin-like Protease/HAT/TMPRSS11D Antibody - NBP1-52138 from Novus Biologicals

Prices	$229.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-TMPRSS11D antibody produced in rabbit - AV46418 from Sigma-Aldrich

Prices	$267.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-TMPRSS11D: <B>Cat. No. AV46418</B>: Immunohistochemistry of TMPRSS11D in Human Lung tissue with TMPRSS11D antibody at 4-8 μg/mL.

Anti-TMPRSS11D antibody produced in mouse - SAB1406820 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-TMPRSS11D: <B>Cat. No. SAB1406820</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~46 kDa using TMPRSS11D transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-TMPRSS11D antibody produced in rabbit - HPA052834 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-TMPRSS11D: <B>Cat. No. HPA052834</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblasts.

Search more