TCP1

Gene Symbol TCP1
Entrez Gene 6950
Alt Symbol CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha
Species Human
Gene Type protein-coding
Description t-complex 1
Other Description T-complex protein 1 subunit alpha|T-complex protein 1, alpha subunit|tailless complex polypeptide 1
Swissprots Q5TCM3 Q15556 E1P5B2 P17987
Accessions AAA61059 AAA61060 EAW47616 EAW47617 EAW47618 P17987 AA810047 AK308551 AK312604 BC000665 AAH00665 BM697304 BM827784 BT006969 AAP35615 DQ890600 ABM92217 DQ893771 ABM84697 X14986 X52882 CAA37064 NM_001008897 NP_001008897 NM_030752 NP_110379
Function Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

TCP-1 α (B-3) - sc-374088 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TCP-1 α (B-3): sc-374088. Western blot analysis of TCP-1 α expression in 293T whole cell lysate.

TCP-1 α (91A) - sc-53454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
TCP-1 α (91A): sc-53454. Western blot analysis of TCP-1 α expression in ECV304 (A), SK-N-SH (B), K-562 (C) and U-937 (D) whole cell lysates.

TCP-1 α (84a ) - sc-53453 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

TCP-1 α (P-15) - sc-13869 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TCP-1 α (P-15): sc-13869. Western blot analysis of TCP-1 a expression in HeLa (A) and ZR-75-1 (B) whole cell lysates and mouse testis extract (C).

TCP-1 α (H-110) - sc-28555 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TCP-1 α (H-110): sc-28555. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing cytoplasmic and nuclear staining of cells in seminiferous ducts, Leydig cells and myoid cells.

TCP-1 α (23c ) - sc-53452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
TCP-1 α (23c): sc-53452. Western blot analysis of TCP-1 α expression in non-transfected 293T: sc-117752 (A), mouse TCP-1 α transfected 293T: sc-123956 (B) and F9 (C) whole cell lysates and mouse testis tissue extract (D).

Anti-TCP1 alpha antibody - ab10180 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TCP1 alpha antibody - ab57684 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
TCP1 alpha antibody (ab57684) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.

Anti-TCP1 alpha antibody - ab123508 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunoprecipitation from HeLa whole cell lysate (1 mg for IP, 20% of IP loaded), using ab123508 at 6 µg/mg lysate for IP Subsequent Western blot detection used an antibody which recognized an downstream epitope of TCP1 alpha at 0.4 µg/ml.Detection: Chemiluminescence with an exposure time of 10 seconds

Anti-TCP1 alpha antibody [22b] - ab31911 from Abcam

Prices $359.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 22b

Anti-TCP1 alpha antibody [EPR4081] - ab92587 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4081
All lanes : Anti-TCP1 alpha antibody [EPR4081] (ab92587) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : ECV-304 cell lysateLane 3 : A459 cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-TCP1 alpha antibody [EPR4082] - ab109126 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4082
All lanes : Anti-TCP1 alpha antibody [EPR4082] (ab109126) at 1/1000 dilutionLane 1 : HeLa cell lysates Lane 2 : ECV-304 cell lysates Lane 3 : MCF7 cell lysates Lane 4 : Daudi cell lysates Lysates/proteins at 10 µg per lane.

Anti-TCP1 alpha antibody - C-terminal - ab185687 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse testis tissue labelling TCP1 alpha with ab185687 at 1/100. Magnification: 200x.

Anti-TCP1 alpha antibody - C-terminal - ab91232 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of TCP1 staining in human testis seminoma formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab91232, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-TCP1 Antibody (C-Terminus) - LS-C18045 from LifeSpan Bioscience

Prices $375.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-TCP1 Antibody (C-Terminus) - LS-C18046 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-TCP1 Antibody (C-Terminus, clone 23c) - LS-C63148 from LifeSpan Bioscience

Prices $295.00, $450.00
Sizes 50 µg, 200 µg
Host Rat
Clonality Monoclonal
Clone 23c

Anti-TCP1 Antibody (C-Terminus) - LS-C90058 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-TCP1 Antibody (C-Terminus, clone 91a) - LS-C63149 from LifeSpan Bioscience

Prices $295.00, $450.00
Sizes 50 µg, 200 µg
Host Rat
Clonality Monoclonal
Clone 91a

Anti-TCP1 Antibody - LS-C132374 from LifeSpan Bioscience

Prices $590.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-TCP1 Antibody (C-Terminus, clone 23c) - LS-C209564 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 23c

Anti-TCP1 Antibody (C-Terminus, clone 91a) - LS-C209565 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 91a

Anti-TCP1 Antibody (C-Terminus, clone 91a, Atto 565) - LS-C229438 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 91a

Anti-TCP1 Antibody (C-Terminus, clone 91a, Atto 594) - LS-C229442 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 91a

Anti-TCP1 Antibody (C-Terminus, clone 91a, Atto 633) - LS-C229443 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 91a
Search more