| Gene Symbol |
TCP1
|
| Entrez Gene |
6950
|
| Alt Symbol |
CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
t-complex 1
|
| Other Description |
T-complex protein 1 subunit alpha|T-complex protein 1, alpha subunit|tailless complex polypeptide 1
|
| Swissprots |
Q5TCM3 Q15556 E1P5B2 P17987
|
| Accessions |
AAA61059 AAA61060 EAW47616 EAW47617 EAW47618 P17987 AA810047 AK308551 AK312604 BC000665 AAH00665 BM697304 BM827784 BT006969 AAP35615 DQ890600 ABM92217 DQ893771 ABM84697 X14986 X52882 CAA37064 NM_001008897 NP_001008897 NM_030752 NP_110379
|
| Function |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}.
|
| Subcellular Location |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
|
![Western Blot: TCP1 alpha Overexpression Lysate (Adult Normal) [NBP2-06194] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TCP1 alpha.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9496_TCP1%2520alpha%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06194-img0001.jpg)