Gene Symbol | TCP1 |
---|---|
Entrez Gene | 6950 |
Alt Symbol | CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha |
Species | Human |
Gene Type | protein-coding |
Description | t-complex 1 |
Other Description | T-complex protein 1 subunit alpha|T-complex protein 1, alpha subunit|tailless complex polypeptide 1 |
Swissprots | Q5TCM3 Q15556 E1P5B2 P17987 |
Accessions | AAA61059 AAA61060 EAW47616 EAW47617 EAW47618 P17987 AA810047 AK308551 AK312604 BC000665 AAH00665 BM697304 BM827784 BT006969 AAP35615 DQ890600 ABM92217 DQ893771 ABM84697 X14986 X52882 CAA37064 NM_001008897 NP_001008897 NM_030752 NP_110379 |
Function | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. |