Gene Symbol | PGLYRP1 |
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Entrez Gene | 8993 |
Alt Symbol | PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L |
Species | Human |
Gene Type | protein-coding |
Description | peptidoglycan recognition protein 1 |
Other Description | TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) |
Swissprots | Q4VB36 O75594 |
Accessions | AAD38243 EAW57400 O75594 AF076483 AAC31822 AF242517 AAF99598 AY358936 AAQ89295 BC096154 AAH96154 BC096155 AAH96155 BC096156 AAH96156 BC096157 AAH96157 BC101845 AAI01846 BC101847 AAI01848 DN998360 NM_005091 NP_005082 |
Function | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:16354652}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:16354652}. Cytoplasmic granule {ECO:0000250}. |
Tissue Specificity | Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:9707603}. |
PGRP-S (H-80) - sc-50472 from Santa Cruz Biotechnology
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PGRP-S (S-14) - sc-55745 from Santa Cruz Biotechnology
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Anti-PGRPS antibody - ab82163 from Abcam
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Anti-PGRPS antibody - ab113625 from Abcam
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Anti-PGRPS antibody - ab172349 from Abcam
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Anti-PGRPS antibody [188C424] - ab13903 from Abcam
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Anti-PGRPS antibody - C-terminal - ab200380 from Abcam
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Anti-PGRPS antibody - C-terminal - ab138424 from Abcam
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Anti-PGLYRP1 / PGRP Antibody (aa146-174) - LS-C323965 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa19-182) - LS-C314971 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa22-196) - LS-C314972 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa147-174) - LS-C158579 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa18-183) - LS-C314973 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa165-180, clone 188C424) - LS-C579 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa179-189) IHC-plus⢠- LS-B4940 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa147-174, APC) - LS-C238947 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (clone 45G1) - LS-C194660 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa147-174, AP) - LS-C238946 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa147-174, Biotin) - LS-C238948 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa147-174, FITC) - LS-C238949 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa147-174, PE) - LS-C238951 from LifeSpan Bioscience
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Anti-PGLYRP1 / PGRP Antibody (aa147-174, Azide-free, HRP) - LS-C248456 from LifeSpan Bioscience
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PGLYRP1/PGRP-S Antibody (188C424) - NB100-56719 from Novus Biologicals
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PGLYRP1/PGRP-S Antibody - NBP1-20962 from Novus Biologicals
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PGLYRP1/PGRP-S Antibody - AF2590 from Novus Biologicals
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