Gene Symbol | PGLYRP1 |
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Entrez Gene | 8993 |
Alt Symbol | PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L |
Species | Human |
Gene Type | protein-coding |
Description | peptidoglycan recognition protein 1 |
Other Description | TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) |
Swissprots | Q4VB36 O75594 |
Accessions | AAD38243 EAW57400 O75594 AF076483 AAC31822 AF242517 AAF99598 AY358936 AAQ89295 BC096154 AAH96154 BC096155 AAH96155 BC096156 AAH96156 BC096157 AAH96157 BC101845 AAI01846 BC101847 AAI01848 DN998360 NM_005091 NP_005082 |
Function | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:16354652}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:16354652}. Cytoplasmic granule {ECO:0000250}. |
Tissue Specificity | Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:9707603}. |
Human PGRPS full length protein - ab175469 from Abcam
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Human PGRPS full length protein - ab160283 from Abcam
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Human PGRPS protein fragment - ab160284 from Abcam
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PGLYRP1 / PGRP Antibody Blocking Peptide - LS-E6022 from LifeSpan Bioscience
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PGLYRP1 / PGRP Antibody Blocking Peptide - LS-E26474 from LifeSpan Bioscience
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PGLYRP1/PGRP-S Partial Recombinant Protein - H00008993-Q01 from Novus Biologicals
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Recombinant Human PGLYRP1/PGRP-S Protein - H00008993-P01 from Novus Biologicals
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PGLYRP1-Antibody-C-term-Blocking-Peptide - BP18597b from Abgent, a WuXi AppTec company
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PGRP-S blocking peptide - GTX88753-PEP from GeneTex
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Recombinant Human PGLYRP1/PGRP-S - 2590-PG-050 from R&D Systems
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Recombinant Human PGLYRP1/PGRP-S, CF - 2590-PG-050/CF from R&D Systems
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Human PGLYRP1 protein - orb191260 from Biorbyt
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Mouse PGLYRP1 His tag protein - orb84484 from Biorbyt
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PGRPS Peptide - AC21-1311-P from Abcore
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PGLYRP1 / PGRPS - H00008993-P01-10 from Acris Antibodies
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PGLYRP1 / PGRPS - H00008993-P01-25 from Acris Antibodies
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PGLYRP1 / PGRPS - H00008993-Q01-10 from Acris Antibodies
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PGLYRP1 / PGRPS - H00008993-Q01-25 from Acris Antibodies
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PGLYRP1 Peptide - 46-886P from ProSci
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PGLYRP1 fusion protein - Ag12690 from Proteintech Group
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Recombinant Human PGLYRP1, His-tagged - PGLYRP1-1667H from Creative Biomart
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Recombinant Human PGLYRP1 Protein, his-tagged - PGLYRP1-732H from Creative Biomart
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Recombinant Human PGLYRP1, His-tagged - PGLYRP1-1041H from Creative Biomart
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Recombinant Peptidoglycan Recognition Protein 1 (PGLYRP1) - RPD937Hu01 from Uscn Life Science Inc.
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Recombinant Peptidoglycan Recognition Protein 1 (PGLYRP1) - RPD937Mu01 from Uscn Life Science Inc.
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