Gene Symbol | KIAA0226 |
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Entrez Gene | 9711 |
Alt Symbol | RUBICON, SCAR15 |
Species | Human |
Gene Type | protein-coding |
Description | KIAA0226 |
Other Description | RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein|RUN domain protein as Beclin 1-interacting and cysteine-rich containing|baron|beclin-1 associated RUN domain containing protein|run domain Beclin-1 interacting and cystein-rich containing protein|run domain Beclin-1 interacting and cysteine-rich containing protein|rundataxin |
Swissprots | Q96CK5 Q92622 |
Accessions | EAW92238 EAW92239 Q92622 AI796534 AK295625 BAG58502 BC014173 AAH14173 BC033615 AAH33615 BC160011 AAI60011 BU501990 BX647598 CAI46107 CN288121 D86979 BAA13215 DA007321 DB036516 DB075342 HY003277 XM_005269374 XP_005269431 XM_006713827 XP_006713890 XM_006713828 XP_006713891 XM_006713829 XP_006713892 XM_006713830 XP_006713893 XM_006713831 XP_006713894 NM_001145642 NP_001139114 NM_014687 NP_055502 |
Function | Negatively regulates endocytic trafficking. Impairs the autophagosome maturation process. May inhibit PIK3C3 activity (By similarity). {ECO:0000250}. |
Subcellular Location | Late endosome {ECO:0000269|PubMed:19270696}. Lysosome {ECO:0000269|PubMed:19270696}. Early endosome {ECO:0000269|PubMed:19270696}. Note=Predominantly located in late endosomes/lysosomes, only partially detected in early endososome and not at all in the Golgi apparatus. |
Human Rubicon full length protein - ab153014 from Abcam
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KIAA0226 / RUBICON Antibody Blocking Peptide - LS-E5779 from LifeSpan Bioscience
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KIAA0226 / RUBICON Antibody Blocking Peptide - LS-E21568 from LifeSpan Bioscience
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Recombinant Human Rubicon Protein - H00009711-P01 from Novus Biologicals
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BARON-Antibody-Center-Blocking-Peptide - BP1831c from Abgent, a WuXi AppTec company
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BARON-Antibody-N-term-Blocking-Peptide - BP1831b from Abgent, a WuXi AppTec company
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BARON-Antibody-N-term-Blocking-Peptide - BP1831a from Abgent, a WuXi AppTec company
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KIAA0226 Blocking Peptide - 33R-2126 from Fitzgerald
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KIAA0226 - H00009711-P01-10 from Acris Antibodies
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KIAA0226 - H00009711-P01-25 from Acris Antibodies
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Rubicon Peptide - 7943P from ProSci
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KIAA0226 fusion protein - Ag13715 from Proteintech Group
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KIAA0226 fusion protein - ag13713 from Proteintech Group
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Recombinant Human Run domain Beclin-1 interacting and cystein-rich containing pr - CSB-YP856415HU CSB-EP856415HU CSB-BP856415HU CSB-MP856415HU from Cusabio
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KIAA0226 (transcript variant 2) - TP320593 from Acris Antibodies
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KIAA0226 Peptide, Human - M34GP08079H from Creative Peptides
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Run domain Beclin-1 interacting and cystein-rich containing protein (KIAA0226), partial, Recombinant Protein - MBS1335276 from MyBioSource
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Recombinant Human KIAA0226 Protein, MYC/DDK-tagged - KIAA0226-406H from Creative Biomart
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