Gene Symbol | KIAA0226 |
---|---|
Entrez Gene | 9711 |
Alt Symbol | RUBICON, SCAR15 |
Species | Human |
Gene Type | protein-coding |
Description | KIAA0226 |
Other Description | RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein|RUN domain protein as Beclin 1-interacting and cysteine-rich containing|baron|beclin-1 associated RUN domain containing protein|run domain Beclin-1 interacting and cystein-rich containing protein|run domain Beclin-1 interacting and cysteine-rich containing protein|rundataxin |
Swissprots | Q96CK5 Q92622 |
Accessions | EAW92238 EAW92239 Q92622 AI796534 AK295625 BAG58502 BC014173 AAH14173 BC033615 AAH33615 BC160011 AAI60011 BU501990 BX647598 CAI46107 CN288121 D86979 BAA13215 DA007321 DB036516 DB075342 HY003277 XM_005269374 XP_005269431 XM_006713827 XP_006713890 XM_006713828 XP_006713891 XM_006713829 XP_006713892 XM_006713830 XP_006713893 XM_006713831 XP_006713894 NM_001145642 NP_001139114 NM_014687 NP_055502 |
Function | Negatively regulates endocytic trafficking. Impairs the autophagosome maturation process. May inhibit PIK3C3 activity (By similarity). {ECO:0000250}. |
Subcellular Location | Late endosome {ECO:0000269|PubMed:19270696}. Lysosome {ECO:0000269|PubMed:19270696}. Early endosome {ECO:0000269|PubMed:19270696}. Note=Predominantly located in late endosomes/lysosomes, only partially detected in early endososome and not at all in the Golgi apparatus. |
KIAA0226 CRISPR/Cas9 KO Plasmid (h) - sc-404222 from Santa Cruz Biotechnology
|
||||||||
KIAA0226 HDR Plasmid (h) - sc-404222-HDR from Santa Cruz Biotechnology
|
||||||||
KIAA0226 Double Nickase Plasmid (h) - sc-404222-NIC from Santa Cruz Biotechnology
|
||||||||
KIAA0226 Double Nickase Plasmid (h2) - sc-404222-NIC-2 from Santa Cruz Biotechnology
|
||||||||
KIAA0226 CRISPR Activation Plasmid (h) - sc-404222-ACT from Santa Cruz Biotechnology
|
||||||||
KIAA0226 CRISPR Activation Plasmid (h2) - sc-404222-ACT-2 from Santa Cruz Biotechnology
|
||||||||
KIAA0226 Lentiviral Activation Particles (h) - sc-404222-LAC from Santa Cruz Biotechnology
|
||||||||
KIAA0226 Lentiviral Activation Particles (h2) - sc-404222-LAC-2 from Santa Cruz Biotechnology
|
||||||||
KIAA0226 siRNA (h) - sc-78326 from Santa Cruz Biotechnology
|
||||||||
KIAA0226 shRNA Plasmid (h) - sc-78326-SH from Santa Cruz Biotechnology
|
||||||||
KIAA0226 shRNA (h) Lentiviral Particles - sc-78326-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU080121 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN11065 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11065 from Sigma-Aldrich
|
||||||||
KIAA0226 siRNA (Human) - CRH6481 from Cohesion Biosciences
|
||||||||
shRNA set against Human KIAA0226 (NM_014687.1) - SHH324511 from Creative biogene
|
||||||||
Human KIAA0226 siRNA - orb266983 from Biorbyt
|
||||||||
KIAA0226 shRNA Plasmid (Human) - CHH6481 from Cohesion Biosciences
|
||||||||