Gene Symbol | GCHFR |
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Entrez Gene | 2644 |
Alt Symbol | GFRP, HsT16933, P35 |
Species | Human |
Gene Type | protein-coding |
Description | GTP cyclohydrolase I feedback regulator |
Other Description | GTP cyclohydrolase 1 feedback regulatory protein|GTP cyclohydrolase I feedback regulatory protein |
Swissprots | B7ZLM8 B2R4L6 P30047 Q99749 Q2M1Q2 |
Accessions | AAB37337 EAW92442 EAW92443 P30047 AK223430 BAD97150 AK311872 BAG34813 BC112262 AAI12263 BC112264 AAI12265 BC143904 AAI43905 HQ258032 ADR82786 NM_005258 NP_005249 |
Function | Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine. {ECO:0000269|PubMed:16778797}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16778797}. Nucleus membrane {ECO:0000269|PubMed:16778797}. Cytoplasm, cytosol {ECO:0000269|PubMed:16778797}. |
Tissue Specificity | In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level). {ECO:0000269|PubMed:16778797}. |
Human GCHFR full length protein - ab158504 from Abcam
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Human GCHFR full length protein - ab180307 from Abcam
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Human GCHFR protein fragment - ab158505 from Abcam
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GCHFR Antibody Blocking Peptide - LS-E16035 from LifeSpan Bioscience
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GCHFR Antibody Blocking Peptide - LS-E6287 from LifeSpan Bioscience
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GCHFR Recombinant Protein - H00002644-P01 from Novus Biologicals
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GCHFR Partial Recombinant Protein - H00002644-Q01 from Novus Biologicals
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GCHFR-Antibody-C-term-Blocking-Peptide - BP18973b from Abgent, a WuXi AppTec company
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GCHFR Blocking Peptide - 33R-6313 from Fitzgerald
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GCHFR protein (His tag) - 80R-3871 from Fitzgerald
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GCHFR / GFRP (1-84, His-tag) - AR51558PU-N from Acris Antibodies
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GCHFR / GFRP (1-84, His-tag) - AR51558PU-S from Acris Antibodies
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GCHFR / GFRP - H00002644-P01-10 from Acris Antibodies
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GCHFR / GFRP - H00002644-P01-25 from Acris Antibodies
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GCHFR / GFRP - H00002644-Q01-10 from Acris Antibodies
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GCHFR / GFRP - H00002644-Q01-25 from Acris Antibodies
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GCHFR, 1-84aa, Human, His tag, E.coli - 01-P2738 from ARP American Research Products
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Recombinant Human GCHFR, His-tagged - GCHFR-245H from Creative Biomart
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Recombinant Human GTP cyclohydrolase 1 feedback regulatory protein(GCHFR) - CSB-YP009318HU CSB-EP009318HU CSB-BP009318HU CSB-MP009318HU from Cusabio
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GCHFR, 1-84aa, Human, His tag, E.coli - ATGP2738 from ATGen
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GCHFR Recombinant Protein Antigen - NBP1-91931PEP from Novus Biologicals
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GTP Cyclohydrolase I Feedback Regulator Protein (Recombinant) - abx261340 from Abbexa
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Human GCHFR protein - orb259900 from Biorbyt
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GCHFR Peptide, Human - M34GP06162H from Creative Peptides
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GCHFR, Recombinant Protein - MBS205666 from MyBioSource
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