GCHFR

Gene Symbol GCHFR
Entrez Gene 2644
Alt Symbol GFRP, HsT16933, P35
Species Human
Gene Type protein-coding
Description GTP cyclohydrolase I feedback regulator
Other Description GTP cyclohydrolase 1 feedback regulatory protein|GTP cyclohydrolase I feedback regulatory protein
Swissprots B7ZLM8 B2R4L6 P30047 Q99749 Q2M1Q2
Accessions AAB37337 EAW92442 EAW92443 P30047 AK223430 BAD97150 AK311872 BAG34813 BC112262 AAI12263 BC112264 AAI12265 BC143904 AAI43905 HQ258032 ADR82786 NM_005258 NP_005249
Function Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine. {ECO:0000269|PubMed:16778797}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16778797}. Nucleus membrane {ECO:0000269|PubMed:16778797}. Cytoplasm, cytosol {ECO:0000269|PubMed:16778797}.
Tissue Specificity In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level). {ECO:0000269|PubMed:16778797}.

GFRP (A-8) - sc-514199 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GFRP (A-8): sc-514199. Western blot analysis of GFRP expression in non-transfected 293T: sc-117752 (A), human GFRP transfected 293T: sc-372605 (B), K-562 (C) and Hep G2 (D) 293T whole cell lysates and human liver tissue extract (E).

GFRP (D-11) - sc-514098 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GFRP (D-11): sc-514098. Western blot analysis of GFRP expression in non-transfected: sc-117752 (A) and human GFRP transfected: sc-372605 (B)293T whole cell lysates.

GFRP (C-16) - sc-22697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GFRP (C-16): sc-22697. Western blot analysis of GFRP expression in non-transfected: sc-117752 (A) and human GFRP transfected: sc-372605 (B) 293T whole cell lysates.

GFRP (FL-84) - sc-368339 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

GFRP (H-16) - sc-22696 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GFRP (H-16): sc-22696. Western blot analysis of GFRP expression in non-transfected: sc-117752 (A) and human GFRP transfected: sc-372605 (B) 293T whole cell lysates.

Anti-GCHFR antibody - ab110161 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab110161, at a 1/50 dilution, staining GCHFR in paraffin embedded Human colon carcinoma tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of the immunizing peptide.

Anti-GCHFR antibody - ab86384 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GCHFR antibody (ab86384) at 1 µg/ml + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-GCHFR Antibody (N-Terminus) - LS-C102041 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GCHFR antibody LS-C102041 Western blot of Fetal Liver lysate.

Anti-GCHFR Antibody (clone 4G6) - LS-C197283 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G6
Detection limit for recombinant GST tagged GCHFR is approximately 0.03 ng/ml as a capture antibody.

Anti-GCHFR Antibody (aa38-66) - LS-C159717 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GCHFR Antibody western blot of K562 cell line lysates (35 ug/lane). The GCHFR antibody detected the GCHFR protein (arrow).

Anti-GCHFR Antibody (aa38-66, Biotin) - LS-C235580 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCHFR Antibody (aa38-66, APC) - LS-C235579 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCHFR Antibody (aa38-66, FITC) - LS-C235581 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCHFR Antibody (aa38-66, AP) - LS-C235577 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCHFR Antibody (aa38-66, PE) - LS-C235582 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCHFR Antibody (aa31-80) - LS-C120019 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human colon carcinoma tissue, using GCHFR Antibody. The picture on the right is treated with the synthesized peptide.

Anti-GCHFR Antibody (aa38-66) - LS-C321582 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCHFR Antibody (aa38-66, Azide-free, HRP) - LS-C249048 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCHFR Antibody - LS-C311167 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

GCHFR Antibody (846011) [Unconjugated] - MAB7918 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 846011
Western blot shows lysates of Hep3B human hepatocellular carcinoma cell line, Bowes human melanoma cell line, and XB2 mouse teratoma keratinocyte cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human GCHFR Monoclonal Antibody (Catalog # MAB7918) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for GCHFR at approximately 11 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

GCHFR Antibody - NBP1-91931 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GCHFR Antibody - NBP1-54960 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GCHFR Antibody [NBP1-54960] - Human Liver cell lysate, concentration 0.2-1 ug/ml.

GCHFR Antibody - H00002644-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GCHFR Antibody [H00002644-D01P] - Analysis of GCHFR expression in transfected 293T cell line by GCHFR polyclonal antibody.Lane 1: GCHFR transfected lysate(9.70 KDa).Lane 2: Non-transfected lysate.

GCHFR Antibody (4G6) - H00002644-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G6
Immunocytochemistry/Immunofluorescence: GCHFR Antibody (4G6) [H00002644-M01] - Analysis of monoclonal antibody to GCHFR on HeLa cell. Antibody concentration 20 ug/ml.

GCHFR Polyclonal Antibody - bs-13313R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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