Gene Symbol | ZBTB18 |
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Entrez Gene | 10472 |
Alt Symbol | C2H2-171, MRD22, RP58, TAZ-1, ZNF238 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger and BTB domain containing 18 |
Other Description | 58 kDa repressor protein|transcriptional repressor RP58|translin-associated zinc finger protein 1|zinc finger and BTB domain-containing protein 18|zinc finger protein 238|zinc finger protein C2H2-171 |
Swissprots | Q9UD99 Q13397 Q5VU40 Q8N463 A8K5U3 Q99592 |
Accessions | CAA11262 EAW77097 EAW77098 EAW77099 Q99592 AJ001388 CAA04718 AK291408 BAF84097 AK293892 BAG57281 AL050055 BC036677 AAH36677 BC078175 CN409673 DC377579 U38896 AAA81368 W68199 X95072 CAA64468 XM_005273006 XP_005273063 NM_001278196 NP_001265125 NM_006352 NP_006343 NM_205768 NP_991331 |
Function | Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus. {ECO:0000269|PubMed:9756912}. |
Subcellular Location | Nucleus. Note=Associates with condensed chromatin. |
Tissue Specificity | Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues. |
RP58 (N-18) - sc-248479 from Santa Cruz Biotechnology
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Anti-ZNF238 antibody - ab103292 from Abcam
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Anti-ZNF238 antibody - ab118471 from Abcam
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Anti-ZNF238 antibody - ab67560 from Abcam
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Anti-ZNF238 antibody - C-terminal - ab157144 from Abcam
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Anti-ZNF238 Antibody (aa143-192) - LS-C169526 from LifeSpan Bioscience
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Anti-ZNF238 Antibody (aa228-498) - LS-C178684 from LifeSpan Bioscience
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Anti-ZNF238 Antibody (aa107-156) IHC-plus⢠- LS-B8070 from LifeSpan Bioscience
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ZNF238 Antibody - H00010472-B01P from Novus Biologicals
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ZNF238 Antibody (4E4) - H00010472-M04 from Novus Biologicals
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ZNF238 Antibody - H00010472-D01P from Novus Biologicals
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Anti-ZNF238 antibody produced in mouse - SAB1406998 from Sigma-Aldrich
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Monoclonal Anti-ZNF238 antibody produced in mouse - SAB1403069 from Sigma-Aldrich
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Anti-ZNF238, (N-terminal) antibody produced in rabbit - SAB2103436 from Sigma-Aldrich
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Anti-ZNF238 (291-305) antibody produced in rabbit - SAB1104359 from Sigma-Aldrich
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Anti-ZNF238 (6-19) antibody produced in rabbit - SAB1104358 from Sigma-Aldrich
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Anti-ZNF238 antibody produced in rabbit - SAB1410094 from Sigma-Aldrich
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ZNF238 antibody - N-terminal region (ARP35799_P050) - ARP35799_P050 from Aviva Systems Biology
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ZNF238 Antibody - N-terminal region (ARP35800_P050) - ARP35800_P050 from Aviva Systems Biology
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ZNF238 antibody - orb78015 from Biorbyt
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ZNF238 antibody - 70R-21399 from Fitzgerald
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ZNF238 Antibody - abx036823 from Abbexa
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ZNF238 antibody - 12714-1-AP from Acris Antibodies
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ZNF238 antibody - H00010472-B01P from Acris Antibodies
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ZNF238 antibody - H00010472-D01P from Acris Antibodies
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