Gene Symbol | ZBTB18 |
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Entrez Gene | 10472 |
Alt Symbol | C2H2-171, MRD22, RP58, TAZ-1, ZNF238 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger and BTB domain containing 18 |
Other Description | 58 kDa repressor protein|transcriptional repressor RP58|translin-associated zinc finger protein 1|zinc finger and BTB domain-containing protein 18|zinc finger protein 238|zinc finger protein C2H2-171 |
Swissprots | Q9UD99 Q13397 Q5VU40 Q8N463 A8K5U3 Q99592 |
Accessions | CAA11262 EAW77097 EAW77098 EAW77099 Q99592 AJ001388 CAA04718 AK291408 BAF84097 AK293892 BAG57281 AL050055 BC036677 AAH36677 BC078175 CN409673 DC377579 U38896 AAA81368 W68199 X95072 CAA64468 XM_005273006 XP_005273063 NM_001278196 NP_001265125 NM_006352 NP_006343 NM_205768 NP_991331 |
Function | Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus. {ECO:0000269|PubMed:9756912}. |
Subcellular Location | Nucleus. Note=Associates with condensed chromatin. |
Tissue Specificity | Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues. |
ZNF238 - MBS1268866 from MyBioSource
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Human ZNF238 cDNA clone(NM_006352.3) - CDFH021806 from Creative Biomart
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human ZNF238 ORF clone - CDCH089066 from Creative Biomart
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human ZNF238 ORF clone - CDCH089067 from Creative Biomart
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human ZNF238 ORF clone - CDCH089068 from Creative Biomart
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human ZNF238 ORF clone - CDCH089069 from Creative Biomart
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human ZNF238 ORF clone - CDCH104914 from Creative Biomart
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human ZNF238 ORF clone - CDCH104915 from Creative Biomart
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human ZNF238 ORF clone - CDCH104916 from Creative Biomart
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human ZNF238 ORF clone - CDCH104917 from Creative Biomart
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Human ZNF238 ORF Clone(NM_006352.3) - CDCL182137 from Creative Biomart
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Human ZNF238 ORF Clone(NM_006352.3) - CDCL182138 from Creative Biomart
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Human ZNF238 ORF Clone(NM_006352.3) - CDCL182139 from Creative Biomart
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Human ZNF238 ORF Clone(NM_006352.3) - CDCR292659 from Creative Biomart
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Human ZNF238 ORF Clone(NM_006352.3) - CDCR292660 from Creative Biomart
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human ZNF238 ORF clone (NM_006352.3) - CDCH089066 from Creative biogene
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human ZNF238 ORF clone (NM_205768.2) - CDCH104914 from Creative biogene
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Human ZNF238 ORF Clone (BC036677) - CDCS412689 from Creative biogene
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Human ZNF238 cDNA Clone(NM_006352.3) - CDFH021806 from Creative biogene
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