REG4

Gene Symbol	REG4
Entrez Gene	83998
Alt Symbol	GISP, REG-IV, RELP
Species	Human
Gene Type	protein-coding
Description	regenerating islet-derived family, member 4
Other Description	REG-4|REG-like protein|gastrointestinal secretory protein|reg IV|regenerating gene type IV|regenerating islet-derived protein 4|regenerating islet-derived protein IV
Swissprots	Q8NER7 Q8NER6 Q9BYZ8
Accessions	CAK22302 EAW56711 EAW56712 EAW56713 EAW56714 Q9BYZ8 AF254415 AAK48435 AF345934 AAK59869 AK057107 AY007243 AAG02562 AY126670 AAM95598 AY126671 AAM95599 AY126672 AAM95600 BC017089 AAH17089 BF242936 DQ891767 ABM82693 DQ894951 ABM85877 NM_001159352 NP_001152824 NM_001159353 NP_001152825 NM_032044 NP_114433
Function	Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. {ECO:0000269|PubMed:12819006, ECO:0000269|PubMed:20692269}.
Subcellular Location	Secreted {ECO:0000269|PubMed:12819006}.
Tissue Specificity	Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. {ECO:0000269|PubMed:11311942, ECO:0000269|PubMed:12455032, ECO:0000269|PubMed:12819006}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

REG4-Over-expression-Lysate - LY15315a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

REG4 293 Cell Lysate - 402725 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Reg4 Overexpression Lysate (Native) - NBL1-15275 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

REG4 Over-expression Lysate Product - GWB-FA74A8 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human REG4 / RELP / GISP CHO Cell Lysate (WB positive control) - 11186-H08SL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human REG4 / RELP / GISP HEK293 Cell Lysate (WB positive control) - 11186-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human REG4 / RELP / GISP HEK293 Cell Lysate (WB positive control) - 11186-H01HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human REG4 Human Cells Transfected Lysate (positive control) (denatured) - orb173342 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Reg4 Overexpression Lysate (Native) - NBP2-10176 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Human REG4 CHO Transfected Lysate (positive control) (denatured) - orb175365 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human REG4 Human Cells Transfected Lysate (positive control) (denatured) - orb174681 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human REG4 Knockdown Stable Cell Line - CSC-DC013153 from Creative biogene Category Cell Line Species Human

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