REG4

Gene Symbol	REG4
Entrez Gene	83998
Alt Symbol	GISP, REG-IV, RELP
Species	Human
Gene Type	protein-coding
Description	regenerating islet-derived family, member 4
Other Description	REG-4|REG-like protein|gastrointestinal secretory protein|reg IV|regenerating gene type IV|regenerating islet-derived protein 4|regenerating islet-derived protein IV
Swissprots	Q8NER7 Q8NER6 Q9BYZ8
Accessions	CAK22302 EAW56711 EAW56712 EAW56713 EAW56714 Q9BYZ8 AF254415 AAK48435 AF345934 AAK59869 AK057107 AY007243 AAG02562 AY126670 AAM95598 AY126671 AAM95599 AY126672 AAM95600 BC017089 AAH17089 BF242936 DQ891767 ABM82693 DQ894951 ABM85877 NM_001159352 NP_001152824 NM_001159353 NP_001152825 NM_032044 NP_114433
Function	Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. {ECO:0000269|PubMed:12819006, ECO:0000269|PubMed:20692269}.
Subcellular Location	Secreted {ECO:0000269|PubMed:12819006}.
Tissue Specificity	Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. {ECO:0000269|PubMed:11311942, ECO:0000269|PubMed:12455032, ECO:0000269|PubMed:12819006}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human REG4 full length protein - ab182679 from Abcam Category Protein Prices $357.00 Sizes 100 µg Source HEK 293 cells Species Human

Human REG4 full length protein - ab63304 from Abcam Category Protein Source E. coli Species Human

Human REG4 full length protein - ab185396 from Abcam Category Protein Source Mammalian Species Human

Human REG4 full length protein - ab202197 from Abcam Category Protein Source E. coli Species Human

Human REG4 full length protein - ab73781 from Abcam Category Protein Source E. coli Species Human

Reg4 Recombinant Protein - H00083998-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Reg4 Recombinant Protein - H00083998-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Reg4, CF - 1379-RG-050 from R&D Systems Category Protein Source E. coli-derived, Asp23-Pro158, with an N-terminal Met

REG4 Protein (OPPA01334) - OPPA01334 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human REG4 protein (His Tag) - orb139585 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source CHO Stable Cells Species Human

Human REG4 protein - orb180396 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human REG4 protein - orb139586 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

REG4 protein (His tag) - 80R-4124 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Human REG4 Protein - abx068844 from Abbexa Category Protein Source E.coli Species Human

REG4 Blocking Peptide - abx161207 from Abbexa Category Peptide Species Human, Mouse, Rat, Pig

REG4 (23-158, His-tag) - AR51810PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

REG4 (23-158, His-tag) - AR51810PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

REG4 - H00083998-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

REG4 - H00083998-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

REG4 - H00083998-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

REG4 - H00083998-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

REG4 - H00083998-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

REG4 - H00083998-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Regenerating Islet-Derived 4, Human Recombinant - 228-11370-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human REG1-IV - 228-11370-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

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