ACVR2B

Gene Symbol	ACVR2B
Entrez Gene	93
Alt Symbol	ACTRIIB, ActR-IIB, HTX4
Species	Human
Gene Type	protein-coding
Description	activin A receptor, type IIB
Other Description	activin receptor type-2B
Swissprots	Q4VAV0 Q13705
Accessions	AAC64515 BAA24180 EAW64536 Q13705 AB209449 BAD92686 AF075005 AAC28458 BC096243 AAH96243 BC096244 AAH96244 BC096245 AAH96245 BC099642 AAH99642 BP352716 X77533 CAA54671 XM_005265583 XP_005265640 NM_001106 NP_001097
Function	Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, activin-B/INHBB as well as inhibin-A/INHA-INHBA). The type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated rece
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Top Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Activin receptor type-2B (ACVR2B), Human, ELISA Kit - E01A1233 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

ACVR2B (Human) IP-WB Antibody Pair - H00000093-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

activin A receptor, type IIB, ELISA Kit - MBS9321527 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.5ng/ml-16ng/ml.

Human ACTR-IIB (Soluble) ELISA KIT - DEIA6918 from Creative Diagnostics Category ELISA Kit Sensitivity 100 pg/mL Range 1.25-80 ng/mL

Activin receptor type 2B (ACVR2B), ELISA Kit - MBS7250486 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Activin receptor type-2B, ELISA Kit - MBS280140 from MyBioSource Category ELISA Kit Prices $425.00, $720.00, $3,160.00, $6,055.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7202818 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7202310 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7215157 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7223367 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7247433 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7208045 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7217305 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7230107 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7205042 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7217383 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin receptor type-2B (ACVR2B), ELISA Kit - MBS7238641 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Custom Human Activin R2B ELISA - ELH-ACVR2B from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human Activin R2B ELISA - RAB1246 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Custom Human Activin R2B ELISA - ELH-ACVR2B-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human ACVR2B ELISA Kit - E000543 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

Activin Receptor Type-2B (ACVR2B), ELISA Kit - MBS9349236 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin Receptor Type-2B (ACVR2B), ELISA Kit - MBS9348738 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin Receptor Type-2B (ACVR2B), ELISA Kit - MBS9363851 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activin Receptor Type-2B (ACVR2B), ELISA Kit - MBS9355368 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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