AES

Gene Symbol	AES
Entrez Gene	166
Alt Symbol	AES-1, AES-2, ESP1, GRG, GRG5, Grg-5, TLE5
Species	Human
Gene Type	protein-coding
Description	amino-terminal enhancer of split
Other Description	gp130-associated protein GAM\|groucho-related protein 5
Swissprots	Q96TG9 B2RBL0 Q9UDY9 Q14CJ1 Q08117 Q12808
Accessions	AAC72103 AAD00654 EAW69341 EAW69342 EAW69343 EAW69344 EAW69345 EAW69346 EAW69347 Q08117 AF072902 AAC35517 AF269289 AAG23172 AK094591 BAG52894 AK095154 AK314713 BAG37257 BC113735 AAI13736 BC113737 AAI13738 BG696926 BG913049 BM550097 BM908356 HQ258149 ADR82903 N23852 U04241 AAA16223 X73357 X73358 CAA51768 XM_006722664 XP_006722727 XM_011527745 XP_011526047 NM_001130 NP_001121 NM_198969 NP_945320 NM_198970 NP_945321
Function	Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. {ECO:0000269\|PubMed:10660609, ECO:0000269\|PubMed:10748198}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver.

TLE5 (C-20) - sc-69045 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TLE5 (N-16) - sc-69046 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TLE5 (S-15) - sc-69047 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TLE5 (T-12) - sc-69048 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

TLE5 (F-G9) - sc-101181 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

TLE5 (F-G9): sc-101181. Western blot analysis of TLE5 expression in HeLa nuclear extract.

Anti-Amino-terminal enhancer of split antibody - ab62555 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Lane 1 : Anti-Amino-terminal enhancer of split antibody (ab62555) at 1 µg/mlLane 2 : Anti-Amino-terminal enhancer of split antibody (ab62555) at 2 µg/mlLane 3 : Anti-Amino-terminal enhancer of split antibody (ab62555) at 4 µg/mlLane 1 : 293 cell lysateLane 2 : 293 cell lysateLane 3 : 293 cell lysateLysates/proteins at 15 µg per lane.

Anti-Amino-terminal enhancer of split antibody - ab16638 from Abcam

Prices	$380.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Amino-terminal enhancer of split antibody (ab16638) at 1 µg/mlLane 1 : As aboveLane 2 : As aboveLane 3 : As aboveLane 4 : As aboveLane 5 : As aboveLane 6 : Human Amino-terminal enhancer of split peptide (ab16684) at 1 µg/mlLane 7 : Human Amino-terminal enhancer of split peptide (ab16684) at 1 µg/mlLane 8 : Human Amino-terminal enhancer of split peptide (ab16684) at 1 µg/mlLane 9 : Human Amino-terminal enhancer of split peptide (ab16684) at 1 µg/mlLane 10 : Human Amino-terminal enhancer of split peptide (ab16684) at 1 µg/mlPerformed under reducing conditions.

Anti-Amino-terminal enhancer of split antibody - ab62556 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Lane 1 : Anti-Amino-terminal enhancer of split antibody (ab62556) at 2 µg/mlLane 2 : Anti-Amino-terminal enhancer of split antibody (ab62556) at 4 µg/mlLane 1 : 293 cell lysateLane 2 : 293 cell lysateLysates/proteins at 15 µg per lane.

Anti-Amino-terminal enhancer of split antibody - ab118280 from Abcam

Prices	$370.00
Sizes	200 µl
Host	Goat
Clonality	Polyclonal

Anti-Amino-terminal enhancer of split antibody (ab118280) at 0.3 µg/ml + Human Cerebral Cortex lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Amino-terminal enhancer of split antibody - ab118881 from Abcam

Prices	$407.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Human skeletal muscle (formalin fixed, paraffin embedded) stained with ab118881 at 2.5 µg/ml, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Amino-terminal enhancer of split antibody - ab54744 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-Amino-terminal enhancer of split antibody - ab171790 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Anti-Amino-terminal enhancer of split antibody [EPR8385] - ab137060 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8385

All lanes : Anti-Amino-terminal enhancer of split antibody [EPR8385] (ab137060) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : PC3 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit IgG at 1/2000 dilution

Anti-AES / Groucho Antibody (N-Terminus) - LS-C3575 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (C-Terminus) - LS-C3574 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (C-Terminus) - LS-C31846 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (aa155-184, APC) - LS-C232461 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (aa155-184, Biotin) - LS-C232462 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (aa155-184, AP) - LS-C232463 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (aa155-184, FITC) - LS-C232464 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (aa155-184, PE) - LS-C232469 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (aa155-184, Azide-free, HRP) - LS-C249384 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody - LS-C309347 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AES / Groucho Antibody (clone 1E1) - LS-C196624 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1E1

Detection limit for recombinant GST tagged AES is approximately 1 ng/ml as a capture antibody.

Anti-AES / Groucho Antibody (aa1-197) - LS-C311794 from LifeSpan Bioscience

Prices	$250.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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