Gene Symbol |
SNAP25
|
Entrez Gene |
6616
|
Alt Symbol |
RIC-4, RIC4, SEC9, SNAP, SNAP-25, bA416N4.2, dJ1068F16.2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
synaptosomal-associated protein, 25kDa
|
Other Description |
SUP|resistance to inhibitors of cholinesterase 4 homolog|super protein|synaptosomal-associated protein 25|synaptosomal-associated protein, 25kD
|
Swissprots |
D3DW17 B2RAU4 Q53EM2 Q5U0B5 P60880 D3DW16
|
Accessions |
EAX10346 EAX10347 EAX10348 EAX10349 EAX10350 EAX10351 EAX10352 EAX10353 P60880 AK026732 AK090857 AK094560 AK098347 AK098767 AK223617 BAD97337 AK289647 BAF82336 AK314359 BAG36991 AM393230 CAL38108 AM393653 CAL38529 BC010647 AAH10647 BI552777 BI602062 BI604120 BT019684 AAV38490 BX647443 D21267 BAA22370 HQ447952 ADQ32436 L19760 AAC37545 L19761 AAC37546 XM_005260808 XP_005260865 XM_005260810 XP_005260867 NM_003081 NP_003072 NM_130811 NP_570824
|
Function |
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
|
Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region (By similarity). {ECO:0000250}.
|
Tissue Specificity |
Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
|
Top Pathways |
Synaptic vesicle cycle
|