Gene Symbol | SNAP25 |
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Entrez Gene | 6616 |
Alt Symbol | RIC-4, RIC4, SEC9, SNAP, SNAP-25, bA416N4.2, dJ1068F16.2 |
Species | Human |
Gene Type | protein-coding |
Description | synaptosomal-associated protein, 25kDa |
Other Description | SUP|resistance to inhibitors of cholinesterase 4 homolog|super protein|synaptosomal-associated protein 25|synaptosomal-associated protein, 25kD |
Swissprots | D3DW17 B2RAU4 Q53EM2 Q5U0B5 P60880 D3DW16 |
Accessions | EAX10346 EAX10347 EAX10348 EAX10349 EAX10350 EAX10351 EAX10352 EAX10353 P60880 AK026732 AK090857 AK094560 AK098347 AK098767 AK223617 BAD97337 AK289647 BAF82336 AK314359 BAG36991 AM393230 CAL38108 AM393653 CAL38529 BC010647 AAH10647 BI552777 BI602062 BI604120 BT019684 AAV38490 BX647443 D21267 BAA22370 HQ447952 ADQ32436 L19760 AAC37545 L19761 AAC37546 XM_005260808 XP_005260865 XM_005260810 XP_005260867 NM_003081 NP_003072 NM_130811 NP_570824 |
Function | t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region (By similarity). {ECO:0000250}. |
Tissue Specificity | Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum. |
Top Pathways | Synaptic vesicle cycle |
C. elegans SNAP25 full length protein - ab51291 from Abcam
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Human SNAP25 full length protein - ab74529 from Abcam
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Human SNAP25 full length protein - ab51048 from Abcam
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Human SNAP25 peptide - ab41724 from Abcam
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Human SNAP25 peptide - ab41725 from Abcam
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SNAP25 full length protein - ab155885 from Abcam
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SNAP25 peptide - ab183130 from Abcam
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SNAP25 peptide - ab183131 from Abcam
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SNAP25 peptide - ab5843 from Abcam
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SNAP25 peptide (193-206) - ab45726 from Abcam
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SNAP25 Antibody Blocking Peptide - LS-E5598 from LifeSpan Bioscience
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SNAP25 Antibody Blocking Peptide - LS-E10720 from LifeSpan Bioscience
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SNAP25 Antibody Blocking Peptide - LS-E25868 from LifeSpan Bioscience
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Recombinant Human SNAP25 Protein - H00006616-P01 from Novus Biologicals
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SNAP25 Partial Recombinant Protein - H00006616-Q01 from Novus Biologicals
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Recombinant C. elegans SNAP25 Protein - NBC1-18330 from Novus Biologicals
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Recombinant Human SNAP25 Protein - NBC1-18333 from Novus Biologicals
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Recombinant Human SNAP25 Protein - NBC1-18344 from Novus Biologicals
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SNAP25 Peptide - NB600-478 from Novus Biologicals
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SNAP25-Antibody-Center-Blocking-Peptide - BP18126c from Abgent, a WuXi AppTec company
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SNAP25 blocking peptide - GTX89577-PEP from GeneTex
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SNAP25 Protein (OPPA01447) - OPPA01447 from Aviva Systems Biology
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SNAP25B Protein (OPPA01765) - OPPA01765 from Aviva Systems Biology
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Human SNAP25 protein (His Tag) - orb81370 from Biorbyt
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Human SNAP25 protein - orb244548 from Biorbyt
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