CIART

Gene Symbol CIART
Entrez Gene 148523
Alt Symbol C1orf51, CHRONO, GM129
Species Human
Gene Type protein-coding
Description circadian associated repressor of transcription
Other Description chIP-derived repressor of network oscillator|circadian-associated transcriptional repressor|computationally highlighted repressor of the network oscillator
Swissprots D3DV01 Q8N795 Q8N365 Q96MG6 B2RD43
Accessions CAI22816 CAI22817 CAI22818 CAI22819 EAW53560 EAW53561 EAW53562 EAW53563 EAW53564 Q8N365 AK056960 BAB71326 AK098755 BAC05404 AK315397 BAG37790 BC017397 AAH17397 BC027999 AAH27999 BC047238 AAH47238 BE784098 CK904668 CN359562 EB388133 GQ129400 ACT64534 GQ129401 ACT64535 HQ447253 ADQ31740 NM_001300838 NP_001287767 NM_001300839 NP_001287768 NM_001300840 NP_001287769 NM_001300841 NP_001287770 NM_144697 NP_653298
Function Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. Rhythmically binds the E-box elements (5'-CACGTG-3') on circadian gene promoters and its occupancy shows circadian oscillation antiphasic to ARNTL/BMAL1. Interacts with the glucocorticoid receptor (NR3C1) and contributes to the repressive function in the glucocorticoid response (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Nucleus, PML body {ECO:0000250}. Note=Co-localizes with the CLOCK-ARNTL/BMAL1 heterodimer in the PML body. {ECO:0000250}.

C1orf51 (D-17) - sc-139577 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

C1orf51 (N-20) - sc-139575 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

C1orf51 (S-20) - sc-139576 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
C1orf51 (S-20): sc-139576. Western blot analysis of C1orf51 expression in non-transfected 293T: sc-117752 (A), human C1orf51 transfected 293T: sc-114702 (B), HeLa (C) and COLO 320DM (D) whole cell lysates and HeLa (E) and COLO 320DM (F) nuclear extracts.

Anti-C1orf51 antibody - ab106120 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-C1orf51 antibody (ab106120) at 1 µg/ml + Human fetal heart lysate at 10 µg

Anti-CIART / C1orf51 Antibody (aa143-192) - LS-C116514 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
C1orf51 antibody LS-C116514 Western blot of Fetal Heart lysate.

Anti-CIART / C1orf51 Antibody (aa25-55) - LS-C168026 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
C1orf51 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human large intestine followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CIART / C1orf51 Antibody (aa25-55, AP) - LS-C233273 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIART / C1orf51 Antibody (aa25-55, APC) - LS-C233274 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIART / C1orf51 Antibody (aa25-55, Biotin) - LS-C233275 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIART / C1orf51 Antibody (aa25-55, FITC) - LS-C233276 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIART / C1orf51 Antibody (aa25-55, PE) - LS-C233277 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIART / C1orf51 Antibody (aa25-55, Azide-free, HRP) - LS-C249550 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CIART / C1orf51 Antibody (aa25-55) - LS-C329285 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

C1orf51 Antibody - NBP1-88685 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf51 Antibody - NBP1-79508 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C1orf51 Antibody [NBP1-79508] - Titration: 0.2-1 ug/ml, Positive Control: Human heart.

C1orf51 Polyclonal Antibody - bs-9786R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-C1ORF51 antibody produced in rabbit - SAB2105869 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C1ORF51: <B>Cat. No. SAB2105869</B>: C1orf51 in Fetal Heart cell lysates with C1orf51 antibody at 1.0 μg/mL.

Anti-C1orf51 (71-85) antibody produced in rabbit - SAB1103560 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C1orf51 was separated on SDS-PAGE, blotted with Anti-C1orf51 (71-85) (<B>Cat. No.SAB1103560</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-C1orf51 antibody produced in rabbit - HPA027515 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-C1ORF51: <B>Cat. No. HPA027515</B>: Immunohistochemical staining of human colon shows cytoplasmic positivity in glandular cells.

Anti-C1orf51 (206-220) antibody produced in rabbit - SAB1103561 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C1orf51 was separated on SDS-PAGE, blotted with Anti-C1orf51 (206-220) (<B>Cat. No.SAB1103561</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500<BR/>2. Antibody dilution 1:500 + C1orf51 immunizing peptide (human, 206-220)

C1orf51 antibody - middle region (ARP52739_P050) - ARP52739_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf51 Antibody - N-terminal region (OAAB00389) - OAAB00389 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

C1orf51-Antibody-N-term - AP10380a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
C1orf51 Antibody (N-term) (Cat. #AP10380a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the C1orf51 antibody detected the C1orf51 protein (arrow).

Anti -C1orf51, NT (C1orf51, Uncharacterized protein C1orf51) - 032850 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -C1orf51, NT (C1orf51, Uncharacterized protein C1orf51) (AP) - 032850-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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