SF3B4

Gene Symbol	SF3B4
Entrez Gene	10262
Alt Symbol	AFD1, Hsh49, SAP49, SF3b49
Species	Human
Gene Type	protein-coding
Description	splicing factor 3b, subunit 4, 49kDa
Other Description	SAP 49|SF3b50|pre-mRNA-splicing factor SF3b 49 kDa subunit|spliceosomal protein|spliceosome-associated protein (U2 snRNP)|spliceosome-associated protein 49|splicing factor 3B subunit 4|splicing factor 3b, subunit 4, 49kD
Swissprots	Q15427 Q5SZ63
Accessions	AAA60300 CAI12553 CAI12554 CAI12647 CAI12648 EAW53595 Q15427 AI925089 AK097315 BAG53452 AK223322 BAD97042 AK310495 BC004273 AAH04273 BC013886 AAH13886 BC090883 AAH90883 BM460550 DA535996 DQ892971 ABM83897 DQ896220 ABM87219 EU176749 ABW03550 NM_005850 NP_005841
Function	Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SF3B4 full length protein - ab132083 from Abcam Category Protein Source Wheat germ Species Human

Human SF3B4 peptide - ab23211 from Abcam Category Peptide Species Human

Human SF3B4 protein fragment - ab160910 from Abcam Category Protein Source Wheat germ Species Human

SF3B4 Antibody Blocking Peptide - LS-E14849 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SF3B4 Antibody Blocking Peptide - LS-E25397 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SF3B4 Antibody Blocking Peptide - LS-E6608 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SF3B4 Protein - H00010262-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SF3B4 Protein - H00010262-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SF3B4-AntibodyCenter-Blocking-peptide - BP19396c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SF3B4 blocking peptide - GTX11803-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

SF3B4 Blocking Peptide - 33R-7491 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SF3B4 Blocking Peptide - 33R-8421 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SF3B4 Peptide - AC21-0225-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SF3B4 / SAP49 - H00010262-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SF3B4 / SAP49 - H00010262-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SF3B4 / SAP49 - H00010262-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SF3B4 / SAP49 - H00010262-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SAP49 Peptide - 46-335P from ProSci Category Peptide Species Human

SF3B4 fusion protein - ag0737 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SF3B4, GST-tagged - SF3B4-2614H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Splicing factor 3B subunit 4(SF3B4) - CSB-YP624024HU CSB-EP624024HU CSB-BP624024HU CSB-MP624024HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SF3B4/SAP49, Peptide - MBS425556 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

SF3B4 Recombinant Protein Antigen - NBP1-83191PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SAP49 Blocking Peptide - abx162035 from Abbexa Category Peptide Species Human, Mouse, Rat

SF3B4 Peptide, Human - M34GP14102H from Creative Peptides Category Peptide Source Synthetic. Species Human

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