DPY30

Gene Symbol DPY30
Entrez Gene 84661
Alt Symbol Cps25, HDPY-30, Saf19
Species Human
Gene Type protein-coding
Description dpy-30 homolog (C. elegans)
Other Description dpy-30-like protein|dpy-30L|protein dpy-30 homolog
Swissprots Q9C005 D6W578
Accessions CAD22967 CAF17541 EAX00463 EAX00464 EAX00465 EAX00466 Q9C005 AF226998 AAK00640 BC015970 AAH15970 BI752326 CD704815 XM_006712117 XP_006712180 XM_006712118 XP_006712181 XM_006712119 XP_006712182 XM_011533133 XP_011531435 NM_032574 NP_115963
Function As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. {ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:19651892, ECO:0000269|PubMed:21335234}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19651892}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:19651892}. Note=Associated with chromatin at regions enriched in histone H3 trimethylated at 'Lys-4. Highly enriched in gene promoter regions and 5' UTRs, but not in downstream regions of genes or 3' UTRs (By similarity). {ECO:0000250}.

DPY-30 CRISPR/Cas9 KO Plasmid (h) - sc-405256 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 HDR Plasmid (h) - sc-405256-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 Double Nickase Plasmid (h) - sc-405256-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 Double Nickase Plasmid (h2) - sc-405256-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 CRISPR Activation Plasmid (h) - sc-405256-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 CRISPR Activation Plasmid (h2) - sc-405256-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 Lentiviral Activation Particles (h) - sc-405256-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 Lentiviral Activation Particles (h2) - sc-405256-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DPY-30 siRNA (h) - sc-94833 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DPY-30 shRNA Plasmid (h) - sc-94833-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DPY-30 shRNA (h) Lentiviral Particles - sc-94833-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU075791 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7478 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7478 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02789 from Sigma-Aldrich

Category miRNA

DPY30 siRNA (Human) - CRJ3564 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DPY30 - MBS8208847 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DPY30 (NM_032574.2) - SHH280849 from Creative biogene

Category siRNA
Species Reactivities Human

DPY30 shRNA Plasmid (Human) - CHJ3564 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DPY30 miRNA 3'UTR clone - MiUTR1H-05862 from Creative biogene

Species Reactivities Human
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