Gene Symbol | DPY30 |
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Entrez Gene | 84661 |
Alt Symbol | Cps25, HDPY-30, Saf19 |
Species | Human |
Gene Type | protein-coding |
Description | dpy-30 homolog (C. elegans) |
Other Description | dpy-30-like protein|dpy-30L|protein dpy-30 homolog |
Swissprots | Q9C005 D6W578 |
Accessions | CAD22967 CAF17541 EAX00463 EAX00464 EAX00465 EAX00466 Q9C005 AF226998 AAK00640 BC015970 AAH15970 BI752326 CD704815 XM_006712117 XP_006712180 XM_006712118 XP_006712181 XM_006712119 XP_006712182 XM_011533133 XP_011531435 NM_032574 NP_115963 |
Function | As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. {ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:19651892, ECO:0000269|PubMed:21335234}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19651892}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:19651892}. Note=Associated with chromatin at regions enriched in histone H3 trimethylated at 'Lys-4. Highly enriched in gene promoter regions and 5' UTRs, but not in downstream regions of genes or 3' UTRs (By similarity). {ECO:0000250}. |
Human DPY30 full length protein - ab135020 from Abcam
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Human DPY30 full length protein - ab183248 from Abcam
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DPY30 protein (His tag) - 80R-3930 from Fitzgerald
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DPY30 (1-99, His-tag) - AR51617PU-N from Acris Antibodies
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DPY30 (1-99, His-tag) - AR51617PU-S from Acris Antibodies
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DPY30 fusion protein - Ag9370 from Proteintech Group
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DPY30, Human Recombinant Protein - GWB-PS06BA from Genway Biotech
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Recombinant Human DPY30, GST-tagged - DPY30-12155H from Creative Biomart
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Recombinant Human Protein dpy-30 homolog(DPY30) - CSB-YP861193HU CSB-EP861193HU CSB-BP861193HU CSB-MP861193HU from Cusabio
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DPY30, 1-99aa, Human, His tag, E.coli - ATGP2797 from ATGen
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Dpy-30 homolog (C. elegans) (DPY30) - TP304981 from Acris Antibodies
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DPY30 Recombinant Protein Antigen - NBP1-91848PEP from Novus Biologicals
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DPY30 Protein (Recombinant) - abx261359 from Abbexa
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DPY30 Peptide, Human - M34GP04531H from Creative Peptides
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Recombinant Human DPY30 Protein - NBP2-51810 from Novus Biologicals
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DPY30 - PAT-82796-1 from Nordic BioSite
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DPY30 - PAT-82796-2 from Nordic BioSite
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DPY30, Human Recombinant - 228-22176-1 from RayBiotech
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DPY30, Recombinant Protein - MBS140900 from MyBioSource
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DPY30, Recombinant Protein - MBS515491 from MyBioSource
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DPY30, Recombinant Protein - MBS205786 from MyBioSource
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Protein dpy-30 homolog (DPY30), Recombinant Protein - MBS1343264 from MyBioSource
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