Gene Symbol | DPY30 |
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Entrez Gene | 84661 |
Alt Symbol | Cps25, HDPY-30, Saf19 |
Species | Human |
Gene Type | protein-coding |
Description | dpy-30 homolog (C. elegans) |
Other Description | dpy-30-like protein|dpy-30L|protein dpy-30 homolog |
Swissprots | Q9C005 D6W578 |
Accessions | CAD22967 CAF17541 EAX00463 EAX00464 EAX00465 EAX00466 Q9C005 AF226998 AAK00640 BC015970 AAH15970 BI752326 CD704815 XM_006712117 XP_006712180 XM_006712118 XP_006712181 XM_006712119 XP_006712182 XM_011533133 XP_011531435 NM_032574 NP_115963 |
Function | As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. {ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:19651892, ECO:0000269|PubMed:21335234}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19651892}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:19651892}. Note=Associated with chromatin at regions enriched in histone H3 trimethylated at 'Lys-4. Highly enriched in gene promoter regions and 5' UTRs, but not in downstream regions of genes or 3' UTRs (By similarity). {ECO:0000250}. |
DPY-30 (D-14) - sc-167677 from Santa Cruz Biotechnology
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Anti-DPY30 antibody - ab126352 from Abcam
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Anti-DPY30 Antibody (aa1-50) - LS-C290935 from LifeSpan Bioscience
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DPY30 Antibody - NBP1-91848 from Novus Biologicals
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DPY30 Antibody - NBP2-32201 from Novus Biologicals
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Anti-DPY30 (11-25) antibody produced in rabbit - SAB1103093 from Sigma-Aldrich
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Anti-DPY30 antibody produced in rabbit - HPA043761 from Sigma-Aldrich
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Anti-DPY30 (21-35) antibody produced in rabbit - SAB1103094 from Sigma-Aldrich
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DPY30 Antibody - N-terminal region (ARP60246_P050) - ARP60246_P050 from Aviva Systems Biology
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DPY30 antibody - 16281-1-AP from Proteintech Group
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DPY30 Antibody - E220004-1 from Enogene
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DPY30 Antibody - E220004-2 from Enogene
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DPY30 Antibody - EPP12440 from Elabscience
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Anti-DPY30 polyclonal antibody - DPABH-22757 from Creative Diagnostics
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DPY30 Antibody - A304-296A from Bethyl Labs
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DPY30, Polyclonal Antibody - MBS2521292 from MyBioSource
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DPY30, Monoclonal Antibody - MBS850855 from MyBioSource
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DPY30 Antibody,Biotin conjugated - CSB-PA861193LD01HU from Cusabio
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DPY30 Antibody,HRP conjugated - CSB-PA861193LB01HU from Cusabio
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DPY30 Antibody,FITC conjugated - CSB-PA861193LC01HU from Cusabio
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DPY30 Antibody - CSB-PA861193LA01HU from Cusabio
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Anti-DPY30 Antibody A06186 - A06186 from Boster Bio
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Hi-Affi™ Recombinant Rabbit Anti-DPY30 Monoclonal Antibody (SI217DS) - MOR-4142 from Creative Biolabs
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DPY30, Polyclonal Antibody - MBS1492797 from MyBioSource
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DPY30, Polyclonal Antibody - MBS1497176 from MyBioSource
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