SHPRH

Gene Symbol	SHPRH
Entrez Gene	257218
Alt Symbol	bA545I5.2
Species	Human
Gene Type	protein-coding
Description	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
Other Description	2610103K11Rik|E3 ubiquitin-protein ligase SHPRH|SNF2, histone-linker, PHD and RING finger domain-containing helicase
Swissprots	Q5VV79 Q149N8 Q68DS5 Q7Z5J5 Q8N1S8 Q8NBR7 Q149N9 Q8IVE8 Q8IWQ9
Accessions	EAW47836 EAW47837 EAW47838 EAW47839 Q149N8 AA315737 AB095943 BAC23119 AK075318 BAC11544 AK094944 BAC04459 AK126959 BAG54410 AK130768 AL833521 AY161136 AAO26201 AY163808 AAO06907 BC113089 AAI13090 BC117685 AAI17686 BC117686 AAI17687 BX648322 CR749290 CAH18145 XM_006715439 XP_006715502 XM_006715440 XP_006715503 XM_006715441 XP_006715504 XM_006715443 XP_006715506 XM_011535719 XP_011534021 XM_011535720 XP_011534022 XM_011535721 XP_011534023 XM_011535722 XP_011534024 XR_245512 XR_942390 XR_942391 XR_942392 XR_942393 XR_942395 NM_001042683 NP_001036148 NM_173082 NP_775105
Function	E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'. {ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:17130289, ECO:0000269|PubMed:18719106}.
Tissue Specificity	Broadly expressed. {ECO:0000269|PubMed:12837266}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SHPRH peptide - ab89391 from Abcam Category Peptide

Human SHPRH protein fragment - ab166079 from Abcam Category Protein Source Wheat germ Species Human

SHPRH Antibody Blocking Peptide - LS-E13087 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SHPRH Protein - H00257218-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SHPRH Blocking Peptide - 33R-8531 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SHPRH - H00257218-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SHPRH - H00257218-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SHPRH fusion protein - Ag16580 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SHPRH fusion protein - ag16635 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SHPRH, His-tagged - SHPRH-2666H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human E3 ubiquitin-protein ligase SHPRH(SHPRH) ,partial - CSB-YP619905HU CSB-EP619905HU CSB-BP619905HU CSB-MP619905HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SHPRH Recombinant Protein Antigen - NBP1-92387PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SHPRH Peptide, Human - M34GP14223H from Creative Peptides Category Peptide Source Synthetic. Species Human

E3 ubiquitin-protein ligase SHPRH (SHPRH), partial, Recombinant Protein - MBS1391717 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

SHPRH Recombinant Protein Antigen - NBP2-55114PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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