DCP1A

Gene Symbol	DCP1A
Entrez Gene	55802
Alt Symbol	HSA275986, Nbla00360, SMAD4IP1, SMIF
Species	Human
Gene Type	protein-coding
Description	decapping mRNA 1A
Other Description	DCP1 decapping enzyme homolog A|Smad4-interacting transcriptional co-activator|decapping enzyme hDcp1a|mRNA-decapping enzyme 1A|putative protein product of Nbla00360|transcription factor SMIF
Swissprots	B4DHN9 U3KQM8 Q9NPI6
Accessions	EAW65283 EAW65284 Q9NPI6 AA129009 AB075507 BAE45754 AJ275986 CAB77023 AK001969 BAA92008 AK025344 AK094470 AK295205 BAG58201 AY146651 AAN62763 BC007439 AAH07439 BC016729 BI769171 BM016520 BP284272 BX481349 CA407150 CD676826 CN289842 DA568874 DA786683 DC371232 DQ893260 ABM84186 DQ896589 ABM87588 NM_001290204 NP_001277133 NM_001290205 NP_001277134 NM_001290206 NP_001277135 NM_001290207 NP_001277136 NM_018403 NP_060873
Function	Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. {ECO:0000269|PubMed:11836524, ECO:0000269|PubMed:12417715}.
Subcellular Location	Cytoplasm, P-body. Nucleus. Note=Co- localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4. {ECO:0000250}.
Tissue Specificity	Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas. {ECO:0000269|PubMed:11836524}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Dcp1a full length protein - ab163233 from Abcam Category Protein Source Wheat germ Species Human

Human Dcp1a peptide - ab71605 from Abcam Category Peptide

Human Dcp1a peptide - ab48045 from Abcam Category Peptide Species Human

Human Dcp1a protein fragment - ab163234 from Abcam Category Protein Source Wheat germ Species Human

SMIF / DCP1A Antibody Blocking Peptide - LS-E4826 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMIF / DCP1A Antibody Blocking Peptide - LS-E12280 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMIF / DCP1A Antibody Blocking Peptide - LS-E14212 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMIF / DCP1A Antibody Blocking Peptide - LS-E26043 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Dcp1a Protein - H00055802-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Dcp1a Protein - H00055802-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

DCP1A-Antibody-N-term-Blocking-Peptide - BP17207a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DCP1A blocking peptide - GTX89354-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

DCP1A Peptide - AC21-0871-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DCP1A - H00055802-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

DCP1A - H00055802-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DCP1A - H00055802-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DCP1A Peptide - 45-467P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

DCP1A fusion protein - Ag18706 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

DCP1A fusion protein - Ag18027 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SMAD4, GST-tagged - DCP1A-7053H from Creative Biomart Category Protein Source E. coli Species Human

SMIF (S133) Peptide - BS2145P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human mRNA-decapping enzyme 1A(DCP1A) - CSB-YP885684HU CSB-EP885684HU CSB-BP885684HU CSB-MP885684HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DCP1A Protein - abx164541 from Abbexa Category Protein Species Human

DCP1A - TP301330 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DCP1A, Peptide - MBS425267 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

Search more