DCP1A

Gene Symbol DCP1A
Entrez Gene 55802
Alt Symbol HSA275986, Nbla00360, SMAD4IP1, SMIF
Species Human
Gene Type protein-coding
Description decapping mRNA 1A
Other Description DCP1 decapping enzyme homolog A|Smad4-interacting transcriptional co-activator|decapping enzyme hDcp1a|mRNA-decapping enzyme 1A|putative protein product of Nbla00360|transcription factor SMIF
Swissprots B4DHN9 U3KQM8 Q9NPI6
Accessions EAW65283 EAW65284 Q9NPI6 AA129009 AB075507 BAE45754 AJ275986 CAB77023 AK001969 BAA92008 AK025344 AK094470 AK295205 BAG58201 AY146651 AAN62763 BC007439 AAH07439 BC016729 BI769171 BM016520 BP284272 BX481349 CA407150 CD676826 CN289842 DA568874 DA786683 DC371232 DQ893260 ABM84186 DQ896589 ABM87588 NM_001290204 NP_001277133 NM_001290205 NP_001277134 NM_001290206 NP_001277135 NM_001290207 NP_001277136 NM_018403 NP_060873
Function Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. {ECO:0000269|PubMed:11836524, ECO:0000269|PubMed:12417715}.
Subcellular Location Cytoplasm, P-body. Nucleus. Note=Co- localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4. {ECO:0000250}.
Tissue Specificity Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas. {ECO:0000269|PubMed:11836524}.
Top Pathways RNA degradation

Dcp1a CRISPR/Cas9 KO Plasmid (h) - sc-402543 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dcp1a HDR Plasmid (h) - sc-402543-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

hDcp1a Double Nickase Plasmid (h) - sc-402543-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dcp1a Double Nickase Plasmid (h2) - sc-402543-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

hDcp1a CRISPR Activation Plasmid (h) - sc-402543-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dcp1a CRISPR Activation Plasmid (h2) - sc-402543-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

hDcp1a Lentiviral Activation Particles (h) - sc-402543-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dcp1a Lentiviral Activation Particles (h2) - sc-402543-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dcp1a siRNA (h) - sc-45779 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dcp1a shRNA Plasmid (h) - sc-45779-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dcp1a shRNA (h) Lentiviral Particles - sc-45779-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dcp1a RNAi - H00055802-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU035941 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6995 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6995 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DCP1A siRNA (Human) - CRJ0934 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DCP1A - MBS8239541 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DCP1A (NM_018403.5) - SHH275253 from Creative biogene

Category siRNA
Species Reactivities Human

Human DCP1A siRNA - orb271435 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DCP1A shRNA Plasmid (Human) - CHJ0934 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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