| Gene Symbol | TYW5 |
|---|---|
| Entrez Gene | 129450 |
| Alt Symbol | C2orf60, hTYW5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | tRNA-yW synthesizing protein 5 |
| Other Description | jmjC domain-containing protein C2orf60|tRNA wybutosine-synthesizing protein 5|tRNA yW-synthesizing enzyme 5|tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase |
| Swissprots | Q8N1R2 B2RNE3 A2RUC4 |
| Accessions | A2RUC4 AAY24162 EAW70191 EAW70192 EAW70193 EAW70194 AK095272 BAC04517 AK293064 BAF85753 AK298977 BAG61071 BC025758 BC063502 AAH63502 BC132835 AAI32836 BC136837 AAI36838 BC144420 BM673915 BX482572 BX647677 BX648265 CB131724 CN261486 HQ258367 ADR83121 HY182974 XM_011510579 XP_011508881 NM_152382 NM_001039693 NP_001034782 NR_004862 NR_109905 NR_109906 NR_109907 |
| Function | tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes. {ECO:0000269|PubMed:20739293}. |
chromosome 2 open reading frame 60, ELISA Kit - MBS9342696 from MyBioSource
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Human C2orf60 ELISA Kit - E008959 from Biobool
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Human TYW5 ELISA Kit - E101714 from Biobool
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