Gene Symbol | TYW5 |
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Entrez Gene | 129450 |
Alt Symbol | C2orf60, hTYW5 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA-yW synthesizing protein 5 |
Other Description | jmjC domain-containing protein C2orf60|tRNA wybutosine-synthesizing protein 5|tRNA yW-synthesizing enzyme 5|tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase |
Swissprots | Q8N1R2 B2RNE3 A2RUC4 |
Accessions | A2RUC4 AAY24162 EAW70191 EAW70192 EAW70193 EAW70194 AK095272 BAC04517 AK293064 BAF85753 AK298977 BAG61071 BC025758 BC063502 AAH63502 BC132835 AAI32836 BC136837 AAI36838 BC144420 BM673915 BX482572 BX647677 BX648265 CB131724 CN261486 HQ258367 ADR83121 HY182974 XM_011510579 XP_011508881 NM_152382 NM_001039693 NP_001034782 NR_004862 NR_109905 NR_109906 NR_109907 |
Function | tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes. {ECO:0000269|PubMed:20739293}. |
Human C2orf60 full length protein - ab139236 from Abcam
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HTYW5 / C2orf60 Antibody Blocking Peptide - LS-E18436 from LifeSpan Bioscience
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HTYW5 / C2orf60 Antibody Blocking Peptide - LS-E18437 from LifeSpan Bioscience
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Recombinant Human TYW5 Protein - NBP2-22891 from Novus Biologicals
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C2orf60-Antibody-Center-Blocking-peptide - BP10306c from Abgent, a WuXi AppTec company
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Human TYW5 protein - orb169498 from Biorbyt
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C2orf60 Blocking Peptide - 33R-6737 from Fitzgerald
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C2orf60 Blocking Peptide - 33R-3782 from Fitzgerald
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TYW5 protein (His tag) - 30R-2915 from Fitzgerald
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C2orf60 (1-315, His-tag) - AR50675PU-N from Acris Antibodies
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C2orf60 (1-315, His-tag) - AR50675PU-S from Acris Antibodies
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TYW5, 1-315aa, Human, His tag, E.coli - 01-P1851 from ARP American Research Products
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C2orf60 fusion protein - Ag23452 from Proteintech Group
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TYW5 Human - PRPS-1322 from NeoScientific
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Human TYW5 Recombinant Protein - GWB-PPAT13 from Genway Biotech
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Recombinant Human TYW5, His-tagged - TYW5-7069H from Creative Biomart
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Recombinant Human tRNA wybutosine-synthesizing protein 5(TYW5) - CSB-YP003860HU CSB-EP003860HU CSB-BP003860HU CSB-MP003860HU from Cusabio
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TYW5, 1-315aa, Human, His tag, E.coli - ATGP1851 from ATGen
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C2orf60 (transcript variant 1) - TP312399 from Acris Antibodies
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TYW5 Recombinant Protein Antigen - NBP1-94109PEP from Novus Biologicals
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TYW5 Peptide, Human - M34GP16921H from Creative Peptides
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TYW5 - PAT-81852-1 from Nordic BioSite
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TYW5 - PAT-81852-2 from Nordic BioSite
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