Gene Symbol | LCP2 |
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Entrez Gene | 3937 |
Alt Symbol | SLP-76, SLP76 |
Species | Human |
Gene Type | protein-coding |
Description | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
Other Description | 76 kDa tyrosine phosphoprotein|SH2 domain-containing leukocyte protein of 76 kDa|SH2 domain-containing leukocyte protein of 76kD|SLP-76 tyrosine phosphoprotein|lymphocyte cytosolic protein 2 |
Swissprots | Q53XV4 A8KA25 Q13094 |
Accessions | AAA93308 EAW61478 EAW61479 EAW61480 Q13094 AK122637 AK292890 BAF85579 AK296098 BAG58851 AK300000 BAG61819 AK310369 BC016618 AAH16618 BG911397 BT007273 AAP35937 DQ890681 ABM81607 DQ893863 ABM84789 FN432830 CBA11531 U20158 AAC50135 XM_011534558 XP_011532860 NM_005565 NP_005556 |
Function | Involved in T-cell antigen receptor mediated signaling. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Tissue Specificity | Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines. |
Top Pathways | Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Osteoclast differentiation, Rap1 signaling pathway |
Human SLP76 full length protein - ab114697 from Abcam
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Human SLP76 full length protein - ab152497 from Abcam
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Human SLP76 peptide - ab45592 from Abcam
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LCP2 / SLP-76 Antibody Blocking Peptide - LS-E25736 from LifeSpan Bioscience
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Recombinant Human SLP-76/LCP2 Protein - H00003937-P01 from Novus Biologicals
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Recombinant Human SLP-76/LCP2 Protein - H00003937-P02 from Novus Biologicals
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SLP76 blocking peptide - GTX17029-PEP from GeneTex
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SLP76 (phospho-Tyr128) Blocking Peptide - abx062869 from Abbexa
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SLP76 Blocking Peptide - abx062870 from Abbexa
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SLP76 Peptide - AC21-0565-P from Abcore
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LCP2 - H00003937-P01-10 from Acris Antibodies
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LCP2 - H00003937-P01-25 from Acris Antibodies
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LCP2 - H00003937-P02 from Acris Antibodies
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LCP2 - H00003937-P02-10 from Acris Antibodies
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LCP2 - H00003937-P02-25 from Acris Antibodies
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LCP2 Peptide - 45-081P from ProSci
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LCP2 fusion protein - Ag3432 from Proteintech Group
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Recombinant Human LCP2 - LCP2-30444TH from Creative Biomart
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Recombinant Lymphocyte Cytosolic Protein 2 (LCP2) - RPB205Mu01 from Uscn Life Science Inc.
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SLP76 (pY128) Blocking Peptide - CBP1675 from Cohesion Biosciences
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SLP76 Blocking Peptide - CBP1676 from Cohesion Biosciences
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SLP-76 (G122) Peptide - BS3758P from Bioworld Technology
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p-SLP-76 (Y128) Peptide - BS4872P from Bioworld Technology
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SLP-76 Peptide - BS5935P from Bioworld Technology
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Recombinant Human Lymphocyte cytosolic protein 2(LCP2) - CSB-YP622635HU CSB-EP622635HU CSB-BP622635HU CSB-MP622635HU from Cusabio
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