Gene Symbol | SDHAF2 |
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Entrez Gene | 54949 |
Alt Symbol | C11orf79, PGL2, SDH5 |
Species | Human |
Gene Type | protein-coding |
Description | succinate dehydrogenase complex assembly factor 2 |
Other Description | SDH assembly factor 2|hSDH5|succinate dehydrogenase assembly factor 2, mitochondrial|succinate dehydrogenase subunit 5, mitochondrial |
Swissprots | Q9NX18 |
Accessions | EAW73951 Q9NX18 AI039966 AI660205 AK000494 BAA91204 BC002331 AAH02331 BX648946 NM_017841 NP_060311 |
Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. {ECO:0000255|HAMAP-Rule:MF_03057, ECO:0000269|PubMed:19628817}. |
Subcellular Location | Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03057, ECO:0000269|PubMed:19628817}. |
SDH5 Antibody - 14445 from Cell Signaling Technology
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SDHAF2 (C-14) - sc-167259 from Santa Cruz Biotechnology
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SDHAF2 (D-12) - sc-167260 from Santa Cruz Biotechnology
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Anti-C11orf79 antibody - ab117448 from Abcam
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Anti-SDHAF2 Antibody (N-Terminus) IHC-plus⢠- LS-B9643 from LifeSpan Bioscience
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PGL2 Antibody - NBP1-92260 from Novus Biologicals
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PGL2 Antibody - NBP1-92259 from Novus Biologicals
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PGL2 Antibody - NBP2-41136 from Novus Biologicals
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Anti-SDHAF2 antibody produced in rabbit - HPA039732 from Sigma-Aldrich
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Anti-SDHAF2 antibody produced in rabbit - HPA039464 from Sigma-Aldrich
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Anti-SDHAF2 antibody produced in chicken - SAB3500641 from Sigma-Aldrich
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SDHAF2 antibody - orb75669 from Biorbyt
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PGL2 / SDHAF2 antibody - 19906-1-AP from Acris Antibodies
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PGL2 / SDHAF2 (N-term) antibody - AP55591PU-N from Acris Antibodies
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PGL2 / SDHAF2 antibody - H00054949-B01P from Acris Antibodies
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SDHAF2 Antibody - 6507 from ProSci
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C11orf79 antibody - 19906-1-AP from Proteintech Group
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C11orf79, Polyclonal Antibody - MBS2517428 from MyBioSource
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SDHAF2 Antibody - 25363 from Signalway Antibody
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C11orf79 Antibody - EPP10966 from Elabscience
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Anti-SDHAF2 (N-terminal) polyclonal antibody - DPAB-L21078 from Creative Diagnostics
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SDHAF2, Polyclonal Antibody - MBS151084 from MyBioSource
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SDHAF2, Polyclonal Antibody - MBS248947 from MyBioSource
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SDHAF2 Antibody - 200-901-EF4 from Rockland Immunochemicals Inc
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Anti-SDHAF2 Antibody - ABS1110 from EMD Millipore
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