Gene Symbol | SDHAF2 |
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Entrez Gene | 54949 |
Alt Symbol | C11orf79, PGL2, SDH5 |
Species | Human |
Gene Type | protein-coding |
Description | succinate dehydrogenase complex assembly factor 2 |
Other Description | SDH assembly factor 2|hSDH5|succinate dehydrogenase assembly factor 2, mitochondrial|succinate dehydrogenase subunit 5, mitochondrial |
Swissprots | Q9NX18 |
Accessions | EAW73951 Q9NX18 AI039966 AI660205 AK000494 BAA91204 BC002331 AAH02331 BX648946 NM_017841 NP_060311 |
Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. {ECO:0000255|HAMAP-Rule:MF_03057, ECO:0000269|PubMed:19628817}. |
Subcellular Location | Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03057, ECO:0000269|PubMed:19628817}. |
Human C11orf79 full length protein - ab139611 from Abcam
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SDHAF2 Blocking Peptide - LS-E31174 from LifeSpan Bioscience
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Recombinant Human PGL2 Protein - NBP2-22834 from Novus Biologicals
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C11orf79-Antibody-C-term-Blocking-peptide - BP10899b from Abgent, a WuXi AppTec company
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SDHAF2 protein (His tag) - 30R-2965 from Fitzgerald
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PGL2 / SDHAF2 (30-166, His-tag) - AR50725PU-N from Acris Antibodies
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PGL2 / SDHAF2 (30-166, His-tag) - AR50725PU-S from Acris Antibodies
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PGL2 / SDHAF2 (N-term) Control Peptide - AP55591CP-N from Acris Antibodies
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SDHAF2, 30-166aa, Human, His tag, E.coli - 01-P1901 from ARP American Research Products
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SDHAF2 Peptide - 6507P from ProSci
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C11orf79 fusion protein - ag17094 from Proteintech Group
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C11orf79 fusion protein - Ag13893 from Proteintech Group
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Human SDHAF2 Recombinant Protein - GWB-PPAT63 from Genway Biotech
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Recombinant Human SDHAF2, His-tagged - SDHAF2-7119H from Creative Biomart
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Recombinant Human Succinate dehydrogenase assembly factor 2, mitochondrial(SDHAF2) - CSB-YP885749HU CSB-EP885749HU CSB-BP885749HU CSB-MP885749HU from Cusabio
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Recombinant Pongo abelii Succinate dehydrogenase assembly factor 2, mitochondri - CSB-YP735662PYX CSB-EP735662PYX CSB-BP735662PYX CSB-MP735662PYX from Cusabio
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SDHAF2, 30-166aa, Human, His tag, E.coli - ATGP1901 from ATGen
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Succinate Dehydrogenase Complex Assembly Factor 2 Protein (Recombinant) - abx261427 from Abbexa
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PGL2 / SDHAF2 - TP301437 from Acris Antibodies
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PGL2 Recombinant Protein Antigen - NBP1-92260PEP from Novus Biologicals
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PGL2 Recombinant Protein Antigen - NBP1-92259PEP from Novus Biologicals
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SDHAF2 Peptide, Human - M34GP13918H from Creative Peptides
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SDHAF2 - PAT-81901-1 from Nordic BioSite
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SDHAF2 - PAT-81901-2 from Nordic BioSite
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Succinate Dehydrogenase Complex Assembly Factor 2, Human Recombinant - 228-22494-1 from RayBiotech
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