RRAGD

Gene Symbol	RRAGD
Entrez Gene	58528
Alt Symbol	RAGD, bA11D8.2.1
Species	Human
Gene Type	protein-coding
Description	Ras-related GTP binding D
Other Description	Rag D protein|ras-related GTP-binding protein D
Swissprots	A8K184 Q7L8F9 Q9NPG0 Q9NQL2
Accessions	EAW48554 Q9NQL2 AF272036 AAG32663 AJ420486 AK126164 AK289799 BAF82488 AL137502 CAB70775 AL523999 BC003088 AAH03088 DB472739 JF432487 ADZ15704 XM_005248755 XP_005248812 XM_011536022 XP_011534324 NM_021244 NP_067067
Function	Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. {ECO:0000269|PubMed:20381137}.
Subcellular Location	Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.
Top Pathways	mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rag D CRISPR/Cas9 KO Plasmid (h) - sc-409310 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D HDR Plasmid (h) - sc-409310-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D Double Nickase Plasmid (h) - sc-409310-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D Double Nickase Plasmid (h2) - sc-409310-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D CRISPR Activation Plasmid (h) - sc-409310-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D CRISPR Activation Plasmid (h2) - sc-409310-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D Lentiviral Activation Particles (h) - sc-409310-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D Lentiviral Activation Particles (h2) - sc-409310-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag D siRNA (h) - sc-95570 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rag D shRNA Plasmid (h) - sc-95570-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rag D shRNA (h) Lentiviral Particles - sc-95570-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU133081 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18679 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18679 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00626 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr00626

RRAGD siRNA (Human) - CRJ1748 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RRAGD - MBS8231424 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human RRAGD (NM_021244.4) - SHH399880 from Creative biogene Category siRNA Species Reactivities Human

Human RRAGD siRNA - orb272249 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RRAGD shRNA Plasmid (Human) - CHJ1748 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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