Gene Symbol | C3 |
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Entrez Gene | 718 |
Alt Symbol | AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p |
Species | Human |
Gene Type | protein-coding |
Description | complement component 3 |
Other Description | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1|C3a anaphylatoxin|acylation-stimulating protein cleavage product|complement C3|complement component C3|complement component C3a|complement component C3b|epididymis secretory sperm binding protein Li 62p|prepro-C3 |
Swissprots | A7E236 P01024 |
Accessions | AAA35722 AAR89906 CAI46844 EAW69070 EAW69071 P01024 AA025232 AI758500 AK094728 AK304071 BAG64978 BC022897 BC063852 BC150179 AAI50180 BC150200 AAI50201 BC150299 BP201387 BP349355 EU794602 ACJ13656 K02765 AAA85332 KC493376 KC493377 M55658 NM_000064 NP_000055 |
Function | C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Plasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods. {ECO:0000269|PubMed:15833747, ECO:0000269|PubMed:9555951}. |
Top Pathways | Phagosome, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection, Complement and coagulation cascades, Pertussis |
C3 (h): 293T Lysate - sc-112683 from Santa Cruz Biotechnology
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C3 (h2): 293T Lysate - sc-112843 from Santa Cruz Biotechnology
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Human Complement C3 Deficient Plasma (EDTA) - D210104 from AssayPro
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Human Complement C3 Deficient Plasma (EDTA) - D210105 from AssayPro
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Human Complement C3 Deficient Plasma (EDTA) - D210106 from AssayPro
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Human Complement C3 Deficient Plasma (Heparin) - D210107 from AssayPro
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Human Complement C3 Deficient Plasma (Heparin) - D210108 from AssayPro
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Human Complement C3 Deficient Plasma (Heparin) - D210109 from AssayPro
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Human Complement C3 Deficient Plasma (Sodium Citrate) - D210101 from AssayPro
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Human Complement C3 Deficient Plasma (Sodium Citrate) - D210102 from AssayPro
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Human Complement C3 Deficient Plasma (Sodium Citrate) - D210103 from AssayPro
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Human Complement C3 Deficient Serum - D210110 from AssayPro
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Human Complement C3 Deficient Serum - D210111 from AssayPro
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Human Complement C3 Deficient Serum - D210112 from AssayPro
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Panoply™ Human C3 Knockdown Stable Cell Line - CSC-DC002019 from Creative biogene
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