NR4A1

Gene Symbol NR4A1
Entrez Gene 3164
Alt Symbol GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 4, group A, member 1
Other Description ST-59|TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|nerve growth factor IB nuclear receptor variant 1|nuclear hormone receptor NUR/77|nuclear receptor subfamily 4 group A member 1|orphan nuclear receptor HMR|orphan nuclear receptor TR3|steroid receptor TR3|testicular receptor 3
Swissprots Q6IBU8 Q15627 B4DML7 P22736 Q53Y00
Accessions CBH19838 EAW58222 EAW58223 EAW58224 EAW58225 EAW58226 EAW58227 EAW58228 P22736 AB307717 BAH02308 AK075054 AK075491 AK096816 AK131566 BAD18699 AK297526 BAG59929 AK314437 BAG37048 AL702926 AL831844 CAD38550 BC016147 AAH16147 BG057763 BT007144 AAP35808 CR456704 CAG32985 D49728 BAA08565 D85245 BAA12746 DQ891134 ABM82060 DQ894313 ABM85239 HQ692855 ADZ17366 L13740 AAA36763 XM_005268822 XP_005268879 XM_005268824 XP_005268881 XM_006719363 XP_006719426 XM_006719364 XP_006719427 XM_011538250 XP_011536552 XM_011538251 XP_011536553 NM_001202233 NP_001189162 NM_001202234 NP_001189163 NM_002135 NP_002126 NM_173157 NP_775180 NM_173158
Function Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. {ECO:0000250, ECO:0000269|PubMed:15466594, ECO:0000269|PubMed:22983157}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Fetal muscle and adult liver, brain and thyroid.
Top Pathways MAPK signaling pathway, PI3K-Akt signaling pathway

Nur77 (h2): 293 Lysate - sc-112240 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

NGFI-B alpha/Nur77/NR4A1 Overexpression Lysate (Native) - NBP2-11329 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NUR77 Overexpression Lysate (Adult Normal) [NBP2-11329] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NUR77.

NGFI-B alpha/Nur77/NR4A1 Overexpression Lysate (Native) - NBP2-10807 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NUR77 Overexpression Lysate (Adult Normal) [NBP2-10807] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NUR77.

NGFI-B alpha/Nur77/NR4A1 Overexpression Lysate (Denatured) - H00003164-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human NR4A1 Knockdown Stable Cell Line - CSC-DC010602 from Creative biogene

Category Cell Line
Species Human
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