NR4A1

Gene Symbol	NR4A1
Entrez Gene	3164
Alt Symbol	GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 4, group A, member 1
Other Description	ST-59|TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|nerve growth factor IB nuclear receptor variant 1|nuclear hormone receptor NUR/77|nuclear receptor subfamily 4 group A member 1|orphan nuclear receptor HMR|orphan nuclear receptor TR3|steroid receptor TR3|testicular receptor 3
Swissprots	Q6IBU8 Q15627 B4DML7 P22736 Q53Y00
Accessions	CBH19838 EAW58222 EAW58223 EAW58224 EAW58225 EAW58226 EAW58227 EAW58228 P22736 AB307717 BAH02308 AK075054 AK075491 AK096816 AK131566 BAD18699 AK297526 BAG59929 AK314437 BAG37048 AL702926 AL831844 CAD38550 BC016147 AAH16147 BG057763 BT007144 AAP35808 CR456704 CAG32985 D49728 BAA08565 D85245 BAA12746 DQ891134 ABM82060 DQ894313 ABM85239 HQ692855 ADZ17366 L13740 AAA36763 XM_005268822 XP_005268879 XM_005268824 XP_005268881 XM_006719363 XP_006719426 XM_006719364 XP_006719427 XM_011538250 XP_011536552 XM_011538251 XP_011536553 NM_001202233 NP_001189162 NM_001202234 NP_001189163 NM_002135 NP_002126 NM_173157 NP_775180 NM_173158
Function	Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. {ECO:0000250, ECO:0000269|PubMed:15466594, ECO:0000269|PubMed:22983157}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Fetal muscle and adult liver, brain and thyroid.
Top Pathways	MAPK signaling pathway, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NUR77 full length protein - ab114314 from Abcam Category Protein Source Wheat germ Species Human

Human NUR77 full length protein - ab114315 from Abcam Category Protein Source Wheat germ Species Human

Human NUR77 peptide - ab96281 from Abcam Category Peptide

Human NUR77 protein fragment - ab152448 from Abcam Category Protein Source Wheat germ Species Human

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E28735 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E8186 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E7351 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E11456 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E11148 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E26163 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E28634 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E28408 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E16644 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR4A1 / NUR77 Antibody Blocking Peptide - LS-E16643 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NGFI-B alpha/Nur77/NR4A1 Protein - H00003164-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NGFI-B alpha/Nur77/NR4A1 Protein - H00003164-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NGFI-B alpha/Nur77/NR4A1 Protein - H00003164-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NGFI-B alpha/Nur77/NR4A1 Peptide - P1914 from Novus Biologicals Category Peptide Species Human

NGFI-B alpha/Nur77/NR4A1 Peptide - P1491 from Novus Biologicals Category Peptide Species Human

Phospho-NR4A1S351-Antibody-Blocking-peptide - BP3339a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

NUR77-NR4A1-Antibody-S351-Blocking-peptide - BP6289c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NUR77 (isoform a) blocking peptide - GTX89206-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

NR4A1 Blocking Peptide - 33R-3032 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NUR77 Blocking Peptide - abx062728 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog

NUR77 Peptide - AC21-0993-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

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