DPH1

Gene Symbol	DPH1
Entrez Gene	1801
Alt Symbol	DPH2L, DPH2L1, OVCA1
Species	Human
Gene Type	protein-coding
Description	diphthamide biosynthesis 1
Other Description	DPH-like 1|DPH1 homolog|DPH2-like 1|candidate tumor suppressor in ovarian cancer 1|diphthamide biosynthesis protein 1|diphthamide biosynthesis protein 2 homolog-like 1|diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1|diptheria toxin resistance protein required for diphthamide biosynthesis-like 1|ovarian cancer-associated gene 1 protein|ovarian tumor suppressor candidate 1
Swissprots	Q9BTW7 Q16439 Q9BZG8 D3DTI3 Q9UCY0 Q4VBA2
Accessions	EAW90566 EAW90567 EAW90569 Q9BZG8 AF321876 AAK13428 AK090530 BAG52179 AK098268 AK297947 BAG60262 AK314015 BAG36726 AL580693 BC003099 AAH03099 BC013205 BC096086 BC096087 BC096088 AAH96088 BC096089 BP417755 BT019878 AAV38681 DQ891858 ABM82784 DQ895047 ABM85973 S81752 AAB36297 U34880 AAD10198 NM_001383 NP_001374
Function	Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10519411}. Cytoplasm {ECO:0000269|PubMed:10519411}. Note=Punctate, primarily perinuclear localization.
Tissue Specificity	Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, mammary gland, colon, small intestine, testis and ovary. Reduced expression in primary breast and ovarian tumors. {ECO:0000269|PubMed:10519411, ECO:0000269|PubMed:8616839}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OVCA1 full length protein - ab158304 from Abcam Category Protein Source Wheat germ Species Human

Human OVCA1 protein fragment - ab158305 from Abcam Category Protein Source Wheat germ Species Human

OVCA1 / DPH1 Antibody Blocking Peptide - LS-E4282 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OVCA1 / DPH1 Antibody Blocking Peptide - LS-E18644 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OVCA1 / DPH1 Antibody Blocking Peptide - LS-E18645 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human OVCA1 Protein - H00001801-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human OVCA1 Protein - H00001801-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DPH1-Antibody-C-term-Blocking-Peptide - BP16559b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DPH1 Blocking Peptide - 33R-8068 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DPH1 Blocking Peptide - 33R-6839 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DPH1 / OVAC1 - H00001801-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DPH1 / OVAC1 - H00001801-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DPH1 / OVAC1 - H00001801-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DPH1 / OVAC1 - H00001801-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

OVCA1 fusion protein - ag13910 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

OVCA1 fusion protein - Ag14041 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Diphthamide biosynthesis protein 1(DPH1) - CSB-YP871625HU CSB-EP871625HU CSB-BP871625HU CSB-MP871625HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DPH1 / OVAC1 - TP321955 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DPH1 Peptide, Human - M34GP04506H from Creative Peptides Category Peptide Source Synthetic. Species Human

Diphthamide biosynthesis protein 1 (DPH1), Recombinant Protein - MBS1425364 from MyBioSource Category Protein Prices $1,220.00, $1,220.00, $1,440.00, $1,440.00, $1,980.00, $1,980.00, $2,445.00, $2,445.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

OVCA1 Recombinant Protein Antigen - NBP2-57765PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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