GPR183

Gene Symbol GPR183
Entrez Gene 1880
Alt Symbol EBI2
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 183
Other Description EBV-induced G-protein coupled receptor 2|Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)|G-protein coupled receptor 183|epstein-Barr virus-induced G-protein coupled receptor 2
Swissprots B2R8N5 Q53F99 P32249 Q5JUH7
Accessions CCF77011 EAX09018 EAX09019 P32249 AI740732 AK223390 BAD97110 AK292091 BAF84780 AK313443 BAG36232 AW402166 AW574697 AW575283 BC020752 AAH20752 DQ891368 ABM82294 DQ894548 ABM85474 L08177 AAA35924 NM_004951 NP_004942
Function Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Binding of 7- alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha. Signals constitutively also via MAPK1/3 (ERK1/2). {ECO:0000250, ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}; Multi-pass membrane protein {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}.
Tissue Specificity Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:8383238}.

Ebi2 (G-12) - sc-514342 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ebi2 (G-12): sc-514342. Western blot analysis of Ebi2 expression in U266 (A) and HeLa (B) whole cell lysates.

Ebi2 (N-20) - sc-66439 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EBI2 (N-20): sc-66439. Western blot analysis of EBI2 expression in Raji (A), U266 (B), U-698-M (C), NAMALWA (D) and Ramos (E) whole cell lysates.

Ebi2 (V-15) - sc-66440 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ebi2 (V-15): sc-66440. Western blot analysis of Ebi2 expression in Jurkat whole cell lysate.

Anti-GPR183 / EBI2 Antibody (aa140-149) - LS-C154806 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-GPR183 / EBI2 Antibody - LS-C307416 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GPR183 / EBI2 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A46 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR183 / EBI2 antibody LS-A46 IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR183 / EBI2 Antibody (aa192-241) - LS-C152171 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GPR183 / EBI2 antibody Western Blot of 293T.

Anti-GPR183 / EBI2 Antibody (Extracellular Domain) IHC-plus™ - LS-A45 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-GPR183 / EBI2 Antibody (aa300-350) - LS-C148722 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of EBI2 in formalin-fixed, paraffin-embedded human stomach tumor tissue using an isotype control (top left) and LS-C148722 (bottom left, right) at 5 ug/ml.

Anti-GPR183 / EBI2 Antibody (C-Terminus) IHC-plus™ - LS-A48 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR183 / EBI2 antibody LS-A48 IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

EBI2/GPR183 Antibody - NBP2-27352 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: EBI2/GPR183 Antibody [NBP2-27352] - Analysis of EBI2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, and 3) rat brain lysate using this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

EBI2/GPR183 Antibody - NLS46 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: EBI2/GPR183 Antibody [NLS46] - Analysis of anti-GPR183 / EBI2 antibody with lymph node.

EBI2/GPR183 Antibody - NLS45 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

EBI2/GPR183 Antibody - NBP1-44160 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

EBI2/GPR183 Antibody - H00001880-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: EBI2/GPR183 Antibody [H00001880-B01] - analysis of EBI2 expression in transfected 293T cell line by EBI2 MaxPab polyclonal antibody (B01). Lane 1: EBI2 transfected lysate (39.82 KDa). Lane 2: Non-transfected lysate.

EBI2/GPR183 Antibody - H00001880-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GPR183 antibody produced in rabbit - HPA028847 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GPR183: <B>Cat. No. HPA028847</B>: Immunohistochemical staining of human placenta shows strong membranous positivity in both decidual and trophoblastic cells.

Anti-GPR183 / EBI2 antibody produced in rabbit - SAB2900584 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GPR183/EBI2 (N-Terminus), antibody produced in rabbit: <B>Cat. No. SAB2900584</B>: Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

GPR183 Antibody - C-terminal region (ARP66371_P050) - ARP66371_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GPR183-Antibody-internal-region - AF3402a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

EBI2 antibody - GTX129712 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-EBI2 (GPR183) antibody used in Western blot. GTX129712

EBI2 (GPR183) antibody [C2C3], C-term - GTX107749 from GeneTex

Host Rabbit
Clonality Polyclonal

EBI2 (GPR183) antibody [N3C2], Internal - GTX100010 from GeneTex

Host Rabbit
Clonality Polyclonal

EBI2 antibody - GTX13319 from GeneTex

Prices $289.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal

EBI2 antibody - GTX70863 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-EBV induced gene 2 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX70863
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