GPR183

Gene Symbol GPR183
Entrez Gene 1880
Alt Symbol EBI2
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 183
Other Description EBV-induced G-protein coupled receptor 2|Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)|G-protein coupled receptor 183|epstein-Barr virus-induced G-protein coupled receptor 2
Swissprots B2R8N5 Q53F99 P32249 Q5JUH7
Accessions CCF77011 EAX09018 EAX09019 P32249 AI740732 AK223390 BAD97110 AK292091 BAF84780 AK313443 BAG36232 AW402166 AW574697 AW575283 BC020752 AAH20752 DQ891368 ABM82294 DQ894548 ABM85474 L08177 AAA35924 NM_004951 NP_004942
Function Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Binding of 7- alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha. Signals constitutively also via MAPK1/3 (ERK1/2). {ECO:0000250, ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}; Multi-pass membrane protein {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}.
Tissue Specificity Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:8383238}.

Human EBV Induced Gene 2 full length protein - ab158331 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158331 on a 12.5% SDS-PAGE stained with Coomassie Blue.

GPR183 / EBI2 Antibody Blocking Peptide - LS-E28995 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

GPR183 / EBI2 Antibody Blocking Peptide - LS-E28971 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

GPR183 / EBI2 Antibody Blocking Peptide - LS-E28980 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

GPR183 / EBI2 Antibody Blocking Peptide - LS-E27547 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GPR183 / EBI2 Antibody Blocking Peptide - LS-E24100 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human EBI2/GPR183 Protein - H00001880-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

EBV Induced Gene 2 Peptide - AC21-2369-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

EBI2 / GPR183 - H00001880-G01 from Acris Antibodies

Category Protein
Prices $440.00
Sizes 2 µg
Species Human

EBI2 / GPR183 - H00001880-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

EBI2 / GPR183 - H00001880-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

GPR183 Peptide - 42-331P from ProSci

Category Peptide

GPR183 fusion protein - Ag3035 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human GPR183, GST-tagged - GPR183-13469H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human GPR183 - GPR183-765H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Human EBI2/GPR183 Protein - H00001880-G01 from Novus Biologicals

Category Protein
Prices $415.00
Sizes 2 µg
Source Wheat Germ
Species Human

GPR183, Peptide - MBS427538 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Bovine, Rabbit

GPR183 Peptide, Human - M34GP06558H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

G-protein coupled receptor 183 (GPR183), Recombinant Protein - MBS954512 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

G-protein coupled receptor 183 (GPR183), Recombinant Protein - MBS7016162 from MyBioSource

Category Protein
Prices $1,170.00, $2,155.00, $3,365.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human

GPR183 Immunizing peptide - orb59722 from Biorbyt

Category Peptide
Prices $247.00
Sizes 100 μg
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