GPR183

Gene Symbol GPR183
Entrez Gene 1880
Alt Symbol EBI2
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 183
Other Description EBV-induced G-protein coupled receptor 2|Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)|G-protein coupled receptor 183|epstein-Barr virus-induced G-protein coupled receptor 2
Swissprots B2R8N5 Q53F99 P32249 Q5JUH7
Accessions CCF77011 EAX09018 EAX09019 P32249 AI740732 AK223390 BAD97110 AK292091 BAF84780 AK313443 BAG36232 AW402166 AW574697 AW575283 BC020752 AAH20752 DQ891368 ABM82294 DQ894548 ABM85474 L08177 AAA35924 NM_004951 NP_004942
Function Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Binding of 7- alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha. Signals constitutively also via MAPK1/3 (ERK1/2). {ECO:0000250, ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}; Multi-pass membrane protein {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:21673108}.
Tissue Specificity Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. {ECO:0000269|PubMed:16540462, ECO:0000269|PubMed:8383238}.

Ebi2 CRISPR/Cas9 KO Plasmid (h) - sc-405397 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 HDR Plasmid (h) - sc-405397-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 Double Nickase Plasmid (h) - sc-405397-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 Double Nickase Plasmid (h2) - sc-405397-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 CRISPR Activation Plasmid (h) - sc-405397-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 CRISPR Activation Plasmid (h2) - sc-405397-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 Lentiviral Activation Particles (h) - sc-405397-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 Lentiviral Activation Particles (h2) - sc-405397-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ebi2 siRNA (h) - sc-62253 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ebi2 shRNA Plasmid (h) - sc-62253-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ebi2 shRNA (h) Lentiviral Particles - sc-62253-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EBI2/GPR183 RNAi - H00001880-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU013381 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9590 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9590 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04507 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04507

GPR183 siRNA (Human) - CRH1314 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPR183 - MBS828468 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GPR183 (NM_004951.4) - SHH306654 from Creative biogene

Category siRNA
Species Reactivities Human

Human GPR183 siRNA - orb261816 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPR183 shRNA Plasmid (Human) - CHH1314 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPR183 miRNA 3'UTR clone - MiUTR3H-07922 from Creative biogene

Species Reactivities Human
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