Gene Symbol | NRG4 |
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Entrez Gene | 145957 |
Alt Symbol | HRG4 |
Species | Human |
Gene Type | protein-coding |
Description | neuregulin 4 |
Other Description | heregulin 4|pro-NRG4|pro-neuregulin-4, membrane-bound isoform |
Swissprots | Q8WWG1 A6NIE8 |
Accessions | EAW99227 EAW99228 Q8WWG1 AK307362 AK311204 AK311507 AM392364 CAL35829 AM392365 CAL35830 AM392366 CAL35831 BC017568 AAH17568 BX538100 CAD98015 CR749519 CAH18333 HQ448724 ADQ33202 NM_138573 NP_612640 |
Function | Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity). {ECO:0000250}. |
Subcellular Location | Pro-neuregulin-4, membrane-bound isoform: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Does not seem to be active. {ECO:0000250}. |
Top Pathways | ErbB signaling pathway |
Neuregulin-4 (N-14) - sc-324162 from Santa Cruz Biotechnology
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Neuregulin-4 (S-15) - sc-324163 from Santa Cruz Biotechnology
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Anti-NRG4 antibody - ab192475 from Abcam
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Anti-NRG4 antibody - ab60090 from Abcam
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Anti-NRG4 Antibody (C-Terminus, APC) - LS-C245135 from LifeSpan Bioscience
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Anti-NRG4 Antibody (C-Terminus, AP) - LS-C245134 from LifeSpan Bioscience
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Anti-NRG4 Antibody (C-Terminus, FITC) - LS-C245137 from LifeSpan Bioscience
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Anti-NRG4 Antibody (C-Terminus, Biotin) - LS-C245136 from LifeSpan Bioscience
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Anti-NRG4 Antibody (C-Terminus, PE) - LS-C245139 from LifeSpan Bioscience
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Anti-NRG4 Antibody (C-Terminus, Azide-free, HRP) - LS-C247722 from LifeSpan Bioscience
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Anti-NRG4 Antibody (C-Terminus) - LS-C330553 from LifeSpan Bioscience
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Anti-NRG4 Antibody - LS-C341449 from LifeSpan Bioscience
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Anti-NRG4 Antibody (aa1-62) - LS-C314907 from LifeSpan Bioscience
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Anti-NRG4 Antibody - LS-C332195 from LifeSpan Bioscience
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NRG4 Antibody - NBP1-81709 from Novus Biologicals
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NRG4 Antibody - H00145957-B01 from Novus Biologicals
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NRG4 Antibody - H00145957-B01P from Novus Biologicals
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Anti-NRG4 antibody produced in mouse - SAB1408905 from Sigma-Aldrich
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Anti-NRG4 antibody produced in rabbit - SAB1408700 from Sigma-Aldrich
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NRG4 antibody - 70R-18964 from Fitzgerald
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NRG4 Polyclonal Antibody - A2599 from ABclonal
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NRG4 Antibody - abx002032 from Abbexa
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Neuregulin 4 antibody - H00145957-B01P from Acris Antibodies
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Neuregulin 4 antibody - H00145957-D01P from Acris Antibodies
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Anti-NRG4 antibody - STJ24820 from St John's Laboratory Ltd
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