NRG4

Gene Symbol NRG4
Entrez Gene 145957
Alt Symbol HRG4
Species Human
Gene Type protein-coding
Description neuregulin 4
Other Description heregulin 4|pro-NRG4|pro-neuregulin-4, membrane-bound isoform
Swissprots Q8WWG1 A6NIE8
Accessions EAW99227 EAW99228 Q8WWG1 AK307362 AK311204 AK311507 AM392364 CAL35829 AM392365 CAL35830 AM392366 CAL35831 BC017568 AAH17568 BX538100 CAD98015 CR749519 CAH18333 HQ448724 ADQ33202 NM_138573 NP_612640
Function Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity). {ECO:0000250}.
Subcellular Location Pro-neuregulin-4, membrane-bound isoform: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Does not seem to be active. {ECO:0000250}.
Top Pathways ErbB signaling pathway

NRG4-Over-expression-Lysate - LY11003a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag NRG4 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NRG4 gene

NRG4 293T Cell Transient Overexpression Lysate(Denatured) - H00145957-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

NRG4 overexpression lysate - LY403362 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

NRG4 Overexpression Lysate (Denatured) - H00145957-T01 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl
Species Human
NRG4 transfected lysate.

NRG4 Overexpression Lysate (Native) - NBP2-04418 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NRG4 Overexpression Lysate (Adult Normal) [NBP2-04418] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NRG4.

Panoply™ Human NRG4 Knockdown Stable Cell Line - CSC-DC010622 from Creative biogene

Category Cell Line
Species Human

NRG4 Knockout Cell Line-HeLa - CSC-RT2083 from Creative biogene

Category Cell Line
Species Human

NRG4 KO Cell Lysate-HeLa - CLKO-1944 from Creative biogene

Category Cell Lysate
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